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Proportion of invasive pneumococcal infections in German children preventable by pneumococcal conjugate vaccines.
von Kries R, Siedler A, Schmitt HJ, Reinert RR. von Kries R, et al. Clin Infect Dis. 2000 Aug;31(2):482-7. doi: 10.1086/313984. Epub 2000 Aug 30. Clin Infect Dis. 2000. PMID: 10987709
The incidence and serotype distribution of Streptococcus pneumoniae as a cause of invasive diseases are unknown with regard to most European countries. ...
The incidence and serotype distribution of Streptococcus pneumoniae as a cause of invasive diseases are unknown with regard to most E …
Epidemiology of pneumococcal disease in children in Germany.
Ziebold C, von Kries R, Siedler A, Schmitt HJ. Ziebold C, et al. Acta Paediatr Suppl. 2000 Dec;89(435):17-21. doi: 10.1111/j.1651-2227.2000.tb00777.x. Acta Paediatr Suppl. 2000. PMID: 11194791
Recently published and as yet unpublished data allow a reasonable estimate of the annual burden of pneumococcal disease in Germany. ...CONCLUSION: Further studies of pneumococcal epidemiology in Germany are needed, and continued surveillance will be necessary for a
Recently published and as yet unpublished data allow a reasonable estimate of the annual burden of pneumococcal disease in Germany. . …
Haemophilus influenzae type b disease: impact and effectiveness of diphtheria-tetanus toxoids-acellular pertussis (-inactivated poliovirus)/H. influenzae type b combination vaccines.
Schmitt HJ, von Kries R, Hassenpflug B, Hermann M, Siedler A, Niessing W, Clemens R, Weil J. Schmitt HJ, et al. Pediatr Infect Dis J. 2001 Aug;20(8):767-74. doi: 10.1097/00006454-200108000-00010. Pediatr Infect Dis J. 2001. PMID: 11734739
These combination vaccines elicit lower anti-Hib antibody concentrations than the equivalent Hib conjugate administered as a separate injection, but the clinical relevance of this phenomenon is unknown. ...During the 2-year study period invasive H. influenzae disease in th …
These combination vaccines elicit lower anti-Hib antibody concentrations than the equivalent Hib conjugate administered as a separate …
Consequences of delayed measles vaccination in Germany.
Siedler A, Hermann M, Schmitt HJ, Von Kries R. Siedler A, et al. Pediatr Infect Dis J. 2002 Sep;21(9):826-30. doi: 10.1097/00006454-200209000-00008. Pediatr Infect Dis J. 2002. PMID: 12352803
According to all three surveillance instruments, the number of measles cases was highest in children age 1 to 4 years with a peak in the second year of life. ...Delayed measles vaccination is responsible for a large number of measles cases still occurring in the Ger …
According to all three surveillance instruments, the number of measles cases was highest in children age 1 to 4 years with a peak in …
Prediction of the potential benefit of different pneumococcal conjugate vaccines on invasive pneumococcal disease in German children.
von Kries R, Hermann M, Hachmeister A, Siedler A, Schmitt HJ, Al-Lahham A, Reinert RR. von Kries R, et al. Pediatr Infect Dis J. 2002 Nov;21(11):1017-23. doi: 10.1097/00006454-200211000-00008. Pediatr Infect Dis J. 2002. PMID: 12442022
BACKGROUND: In the US a pneumococcal conjugate vaccination program with a 7-valent conjugate vaccine was successfully implemented in 2000. ...RESULTS: A total of 1,743 cases were reported; 667 isolates were serotyped. Coverage of 7-valent (11-valent) conjugat …
BACKGROUND: In the US a pneumococcal conjugate vaccination program with a 7-valent conjugate vaccine was successfully implemen …
Will the 7-valent pneumococcal vaccine have a similar impact on all invasive pneumococcal infections in children in Germany as in the Kaiser Permanente Trial?
von Kries R, Hermann M, Al-Lahham A, Siedler A, Reinert RR. von Kries R, et al. Eur J Pediatr. 2002 Dec;161 Suppl 2:S140-3. doi: 10.1007/s00431-002-1067-9. Epub 2002 Oct 2. Eur J Pediatr. 2002. PMID: 12494261
A 7-valent pneumococcal conjugate (7-vPc) vaccine was shown to be highly effective in California preventing 89.1% of all invasive pneumococcal infections (IPI) regardless of serotype. There is concern whether a similar effectiveness will be attained in Germany where
A 7-valent pneumococcal conjugate (7-vPc) vaccine was shown to be highly effective in California preventing 89.1% of all invasive pne
Progress toward measles elimination in Germany.
Hellenbrand W, Siedler A, Tischer A, Meyer C, Reiter S, Rasch G, Teichmann D, Santibanez S, Altmann D, Claus H, Kramer M. Hellenbrand W, et al. J Infect Dis. 2003 May 15;187 Suppl 1:S208-16. doi: 10.1086/368046. J Infect Dis. 2003. PMID: 12721915 Review.
While the former East Germany (FEG) achieved a reduction of measles incidence to <1 case per 100,000 population before reunification in 1990, the former West Germany (FWG) experienced significant measles morbidity. ...Recent establishment of comprehensive nationwide sur …
While the former East Germany (FEG) achieved a reduction of measles incidence to <1 case per 100,000 population before reunificati …
Laboratory investigations are indispensable to monitor the progress of measles elimination--results of the German Measles Sentinel 1999-2003.
Tischer A, Santibanez S, Siedler A, Heider A, Hengel H. Tischer A, et al. J Clin Virol. 2004 Nov;31(3):165-78. doi: 10.1016/j.jcv.2004.05.007. J Clin Virol. 2004. PMID: 15465408
BACKGROUND: The elimination of measles is a goal set by the World Health Organisation to be reached by 2010 in the European region. OBJECTIVES: To enhance the measles surveillance in Germany, a country-wide laboratory supported a sentinel was established. STU …
BACKGROUND: The elimination of measles is a goal set by the World Health Organisation to be reached by 2010 in the European region. O …
Antibiotic susceptibility in neonatal invasive isolates of Streptococcus agalactiae in a 2-year nationwide surveillance study in Germany.
Fluegge K, Supper S, Siedler A, Berner R. Fluegge K, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4444-6. doi: 10.1128/AAC.48.11.4444-4446.2004. Antimicrob Agents Chemother. 2004. PMID: 15504878 Free PMC article.
The antimicrobial susceptibility of 296 invasive neonatal group B streptococcus isolates from a nationwide 2-year surveillance study in Germany was investigated. ...
The antimicrobial susceptibility of 296 invasive neonatal group B streptococcus isolates from a nationwide 2-year surveillance study …
Four and one-half-year follow-up of the effectiveness of diphtheria-tetanus toxoids-acellular pertussis/Haemophilus influenzae type b and diphtheria-tetanus toxoids-acellular pertussis-inactivated poliovirus/H. influenzae type b combination vaccines in Germany.
Kalies H, Verstraeten T, Grote V, Meyer N, Siedler A, Schmitt HJ, Breuer T, Moulton LH, von Kries R; Erhebungseinheit für seltene pädiatrische Erkrankungen in Deutschland Study Group. Kalies H, et al. Pediatr Infect Dis J. 2004 Oct;23(10):944-50. doi: 10.1097/01.inf.0000141743.74443.73. Pediatr Infect Dis J. 2004. PMID: 15602195
A representative subcohort of 667 children born in the same time frame was randomly sampled in a nationwide vaccine coverage survey. ...VE of combination vaccines against invasive Hib infection was 89.6% [95% confidence interval (CI), 67.0-96.7] for an incomplete pr
A representative subcohort of 667 children born in the same time frame was randomly sampled in a nationwide vaccine coverage s
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