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Platelet-derived growth factor is angiogenic in vivo.
Risau W, Drexler H, Mironov V, Smits A, Siegbahn A, Funa K, Heldin CH. Risau W, et al. Among authors: siegbahn a. Growth Factors. 1992;7(4):261-6. doi: 10.3109/08977199209046408. Growth Factors. 1992. PMID: 1284870
Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis.
Rönnstrand L, Siegbahn A, Rorsman C, Johnell M, Hansen K, Heldin CH. Rönnstrand L, et al. Among authors: siegbahn a. J Biol Chem. 1999 Jul 30;274(31):22089-94. doi: 10.1074/jbc.274.31.22089. J Biol Chem. 1999. PMID: 10419537
We have previously shown that porcine aortic endothelial cells expressing the Y934F platelet-derived growth factor (PDGF) beta-receptor mutant respond to PDGF-BB in a chemotaxis assay at about 100-fold lower concentration than do wild-type PDGF beta-receptor-expressing cel …
We have previously shown that porcine aortic endothelial cells expressing the Y934F platelet-derived growth factor (PDGF) beta-receptor muta …
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