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Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF.
Song YJ, Choi IA, Meylan F, Demoruelle MK, Farley T, Richard AC, Hawley E, Botson J, Hong YJ, Lee EY, Mian SR, Hamilton BC, Thiele GM, Mikuls TR, Gara N, Ward CD, Lamberth S, Deane KD, Heller T, Ward MM, Lee DM, Migone TS, Stohl W, O'Dell JR, Norris JM, Holers VM, Gregersen P, Song YW, Siegel RM. Song YJ, et al. Among authors: siegel rm. Arthritis Res Ther. 2020 May 7;22(1):106. doi: 10.1186/s13075-020-02198-9. Arthritis Res Ther. 2020. PMID: 32381123 Free PMC article.
The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.
Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, O'Shea JJ, Al-Shamkhani A, Kaplan MH, Gery I, Siegel RM, Meylan F. Richard AC, et al. Among authors: siegel rm. J Immunol. 2015 Apr 15;194(8):3567-82. doi: 10.4049/jimmunol.1401220. Epub 2015 Mar 18. J Immunol. 2015. PMID: 25786692 Free PMC article.
The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation.
Meylan F, Song YJ, Fuss I, Villarreal S, Kahle E, Malm IJ, Acharya K, Ramos HL, Lo L, Mentink-Kane MM, Wynn TA, Migone TS, Strober W, Siegel RM. Meylan F, et al. Among authors: siegel rm. Mucosal Immunol. 2011 Mar;4(2):172-85. doi: 10.1038/mi.2010.67. Epub 2010 Oct 27. Mucosal Immunol. 2011. PMID: 20980995 Free PMC article.
244 results