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Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers.
Liu DT, Tibbs GR, Paoletti P, Siegelbaum SA. Liu DT, et al. Among authors: siegelbaum sa. Neuron. 1998 Jul;21(1):235-48. doi: 10.1016/s0896-6273(00)80530-9. Neuron. 1998. PMID: 9697867
Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP.
Hu L, Santoro B, Saponaro A, Liu H, Moroni A, Siegelbaum S. Hu L, et al. J Gen Physiol. 2013 Dec;142(6):599-612. doi: 10.1085/jgp.201311013. J Gen Physiol. 2013. PMID: 24277603 Free PMC article.
A cortico-hippocampal learning rule shapes inhibitory microcircuit activity to enhance hippocampal information flow.
Basu J, Srinivas KV, Cheung SK, Taniguchi H, Huang ZJ, Siegelbaum SA. Basu J, et al. Among authors: siegelbaum sa. Neuron. 2013 Sep 18;79(6):1208-21. doi: 10.1016/j.neuron.2013.07.001. Neuron. 2013. PMID: 24050406 Free PMC article.
Strong CA2 pyramidal neuron synapses define a powerful disynaptic cortico-hippocampal loop.
Chevaleyre V, Siegelbaum SA. Chevaleyre V, et al. Among authors: siegelbaum sa. Neuron. 2010 May 27;66(4):560-72. doi: 10.1016/j.neuron.2010.04.013. Neuron. 2010. PMID: 20510860 Free PMC article.
Recruitment of N-Type Ca(2+) channels during LTP enhances low release efficacy of hippocampal CA1 perforant path synapses.
Ahmed MS, Siegelbaum SA. Ahmed MS, et al. Among authors: siegelbaum sa. Neuron. 2009 Aug 13;63(3):372-85. doi: 10.1016/j.neuron.2009.07.013. Neuron. 2009. PMID: 19679076 Free PMC article.
A role for synaptic inputs at distal dendrites: instructive signals for hippocampal long-term plasticity.
Dudman JT, Tsay D, Siegelbaum SA. Dudman JT, et al. Among authors: siegelbaum sa. Neuron. 2007 Dec 6;56(5):866-79. doi: 10.1016/j.neuron.2007.10.020. Neuron. 2007. PMID: 18054862 Free PMC article.
Making the grade with models of persistent activity.
Dudman JT, Siegelbaum SA. Dudman JT, et al. Among authors: siegelbaum sa. Neuron. 2006 Mar 2;49(5):649-51. doi: 10.1016/j.neuron.2006.02.010. Neuron. 2006. PMID: 16504940
Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses.
Zakharenko SS, Patterson SL, Dragatsis I, Zeitlin SO, Siegelbaum SA, Kandel ER, Morozov A. Zakharenko SS, et al. Among authors: siegelbaum sa. Neuron. 2003 Sep 11;39(6):975-90. doi: 10.1016/s0896-6273(03)00543-9. Neuron. 2003. PMID: 12971897
The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells.
Nolan MF, Malleret G, Lee KH, Gibbs E, Dudman JT, Santoro B, Yin D, Thompson RF, Siegelbaum SA, Kandel ER, Morozov A. Nolan MF, et al. Among authors: siegelbaum sa. Cell. 2003 Nov 26;115(5):551-64. doi: 10.1016/s0092-8674(03)00884-5. Cell. 2003. PMID: 14651847
Recurrent circuitry dynamically shapes the activation of piriform cortex.
Franks KM, Russo MJ, Sosulski DL, Mulligan AA, Siegelbaum SA, Axel R. Franks KM, et al. Among authors: siegelbaum sa. Neuron. 2011 Oct 6;72(1):49-56. doi: 10.1016/j.neuron.2011.08.020. Neuron. 2011. PMID: 21982368 Free PMC article.
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