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Leptin: a pivotal mediator of intestinal inflammation in mice.
Siegmund B, Lehr HA, Fantuzzi G. Siegmund B, et al. Gastroenterology. 2002 Jun;122(7):2011-25. doi: 10.1053/gast.2002.33631. Gastroenterology. 2002. PMID: 12055606
Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.
Jones-Carson J, Fantuzzi G, Siegmund B, Dinarello C, Tracey KJ, Wang H, Fang FC, Vazquez-Torres A. Jones-Carson J, et al. Among authors: siegmund b. J Infect Dis. 2005 Sep 15;192(6):1039-46. doi: 10.1086/432727. Epub 2005 Aug 4. J Infect Dis. 2005. PMID: 16107957
Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein.
Siegmund B, Sennello JA, Lehr HA, Senaldi G, Dinarello CA, Fantuzzi G. Siegmund B, et al. Eur J Immunol. 2004 Sep;34(9):2356-64. doi: 10.1002/eji.200425124. Eur J Immunol. 2004. PMID: 15307168
Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
Fantuzzi G, Banda NK, Guthridge C, Vondracek A, Kim SH, Siegmund B, Azam T, Sennello JA, Dinarello CA, Arend WP. Fantuzzi G, et al. Among authors: siegmund b. J Leukoc Biol. 2003 Nov;74(5):889-96. doi: 10.1189/jlb.0503230. Epub 2003 Aug 11. J Leukoc Biol. 2003. PMID: 12960225
Neutrophil-independent mechanisms of caspase-1- and IL-18-mediated ischemic acute tubular necrosis in mice.
Melnikov VY, Faubel S, Siegmund B, Lucia MS, Ljubanovic D, Edelstein CL. Melnikov VY, et al. Among authors: siegmund b. J Clin Invest. 2002 Oct;110(8):1083-91. doi: 10.1172/JCI15623. J Clin Invest. 2002. PMID: 12393844 Free PMC article.
Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation.
Siegmund B. Siegmund B. Biochem Pharmacol. 2002 Jul 1;64(1):1-8. doi: 10.1016/s0006-2952(02)01064-x. Biochem Pharmacol. 2002. PMID: 12106600 Review.
Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis.
Siegmund B, Lear-Kaul KC, Faggioni R, Fantuzzi G. Siegmund B, et al. Eur J Immunol. 2002 Feb;32(2):552-60. doi: 10.1002/1521-4141(200202)32:2<552::AID-IMMU552>3.0.CO;2-H. Eur J Immunol. 2002. PMID: 11828372
Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1.
Wieland CW, Siegmund B, Senaldi G, Vasil ML, Dinarello CA, Fantuzzi G. Wieland CW, et al. Among authors: siegmund b. Infect Immun. 2002 Mar;70(3):1352-8. doi: 10.1128/iai.70.3.1352-1358.2002. Infect Immun. 2002. PMID: 11854220 Free PMC article.
Development of intestinal inflammation in double IL-10- and leptin-deficient mice.
Siegmund B, Sennello JA, Lehr HA, Batra A, Fedke I, Zeitz M, Fantuzzi G. Siegmund B, et al. J Leukoc Biol. 2004 Oct;76(4):782-6. doi: 10.1189/jlb.0404239. Epub 2004 Jul 7. J Leukoc Biol. 2004. PMID: 15240754
IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.
Siegmund B, Lehr HA, Fantuzzi G, Dinarello CA. Siegmund B, et al. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13249-54. doi: 10.1073/pnas.231473998. Epub 2001 Oct 23. Proc Natl Acad Sci U S A. 2001. PMID: 11606779 Free PMC article.
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