Siegmund W - Search Results

1

Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses.

Garbacz G, Wedemeyer RS, Nagel S, Giessmann T, Mönnikes H, Wilson CG, Siegmund W, Weitschies W. Garbacz G, et al. Among authors: siegmund w. Eur J Pharm Biopharm. 2008 Oct;70(2):421-8. doi: 10.1016/j.ejpb.2008.05.029. Epub 2008 Jun 7. Eur J Pharm Biopharm. 2008. PMID: 18582568

2

Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein.

Westphal K, Weinbrenner A, Giessmann T, Stuhr M, Franke G, Zschiesche M, Oertel R, Terhaag B, Kroemer HK, Siegmund W. Westphal K, et al. Among authors: siegmund w. Clin Pharmacol Ther. 2000 Jul;68(1):6-12. doi: 10.1067/mcp.2000.107579. Clin Pharmacol Ther. 2000. PMID: 10945310 Clinical Trial.

3

[The challenge of patient consultation and pharmaceutical development: bisphosphonate in solid dosage forms].

Weitschies W, Siegmund W. Weitschies W, et al. Among authors: siegmund w. Pharm Unserer Zeit. 2001;30(6):536-40. doi: 10.1002/1615-1003(200111)30:6<536::AID-PAUZ536>3.0.CO;2-H. Pharm Unserer Zeit. 2001. PMID: 11715687 Review. German. No abstract available.

4

Requirements concerning antiseptics for periorbital, orbital and intraorbital application. Systemic tolerance of antiseptics used in ophthalmology.

Siegmund W, Giessmann T. Siegmund W, et al. Dev Ophthalmol. 2002;33:57-65. doi: 10.1159/000065919. Dev Ophthalmol. 2002. PMID: 12236128 Review. No abstract available.

5

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

Siegmund W, Ludwig K, Giessmann T, Dazert P, Schroeder E, Sperker B, Warzok R, Kroemer HK, Cascorbi I. Siegmund W, et al. Clin Pharmacol Ther. 2002 Nov;72(5):572-83. doi: 10.1067/mcp.2002.127739. Clin Pharmacol Ther. 2002. PMID: 12426521

6

Variability of intestinal expression of P-glycoprotein in healthy volunteers as described by absorption of talinolol from four bioequivalent tablets.

Siegmund W, Ludwig K, Engel G, Zschiesche M, Franke G, Hoffmann A, Terhaag B, Weitschies W. Siegmund W, et al. J Pharm Sci. 2003 Mar;92(3):604-10. doi: 10.1002/jps.10327. J Pharm Sci. 2003. PMID: 12587122 Clinical Trial.

7

[Significance of drug transporter for the internal medicine clinic].

Siegmund W, Cascorbi I, Weitschies W, Kroemer HK. Siegmund W, et al. Internist (Berl). 2003 Feb;44(2):219-26. Internist (Berl). 2003. PMID: 12674742 German. No abstract available.

8

Effects of fatty acids on hepatic amino acid catabolism and fibrinogen synthesis in young healthy volunteers.

Freyse EJ, Giessmann T, Petzke KJ, Knospe S, Engel G, Heinke P, Metges CC, Siegmund W. Freyse EJ, et al. Among authors: siegmund w. Am J Physiol Endocrinol Metab. 2003 Jul;285(1):E54-62. doi: 10.1152/ajpendo.00324.2002. Am J Physiol Endocrinol Metab. 2003. PMID: 12791602 Free article. Clinical Trial.

9

CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects.

Giessmann T, Modess C, Hecker U, Zschiesche M, Dazert P, Kunert-Keil C, Warzok R, Engel G, Weitschies W, Cascorbi I, Kroemer HK, Siegmund W. Giessmann T, et al. Among authors: siegmund w. Clin Pharmacol Ther. 2004 Mar;75(3):213-22. doi: 10.1016/j.clpt.2003.10.004. Clin Pharmacol Ther. 2004. PMID: 15001973

10

Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14 : 1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism.

Siegmund W, Spieker K, Weike AI, Giessmann T, Modess C, Dabers T, Kirsch G, Sänger E, Engel G, Hamm AO, Nauck M, Meng W. Siegmund W, et al. Clin Endocrinol (Oxf). 2004 Jun;60(6):750-7. doi: 10.1111/j.1365-2265.2004.02050.x. Clin Endocrinol (Oxf). 2004. PMID: 15163340 Clinical Trial.

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