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CTLA4-Ig-Based Bifunctional Costimulation Inhibitor Blocks CD28 and ICOS Signaling to Prevent T Cell Priming and Effector Function.
Goenka R, Xu Z, Samayoa J, Banach D, Beam C, Bose S, Dooner G, Forsyth CM, Lu X, Medina L, Sadhukhan R, Sielaff B, Sousa S, Tao Q, Touw D, Wu F, Kingsbury GA, Akamatsu Y. Goenka R, et al. Among authors: sielaff b. J Immunol. 2021 Mar 1;206(5):1102-1113. doi: 10.4049/jimmunol.2001100. Epub 2021 Jan 25. J Immunol. 2021. PMID: 33495237 Free article.
CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches.
Argiriadi MA, Benatuil L, Dubrovska I, Egan DA, Gao L, Greischar A, Hardman J, Harlan J, Iyer RB, Judge RA, Lake M, Perron DC, Sadhukhan R, Sielaff B, Sousa S, Wang R, McRae BL. Argiriadi MA, et al. Among authors: sielaff b. BMC Mol Cell Biol. 2019 Aug 5;20(1):29. doi: 10.1186/s12860-019-0213-4. BMC Mol Cell Biol. 2019. PMID: 31382872 Free PMC article.
Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Todorović V, Su Z, Putman CB, Kakavas SJ, Salte KM, McDonald HA, Wetter JB, Paulsboe SE, Sun Q, Gerstein CE, Medina L, Sielaff B, Sadhukhan R, Stockmann H, Richardson PL, Qiu W, Argiriadi MA, Henry RF, Herold JM, Shotwell JB, McGaraughty SP, Honore P, Gopalakrishnan SM, Sun CC, Scott VE. Todorović V, et al. Among authors: sielaff b. Sci Rep. 2019 Jun 24;9(1):9089. doi: 10.1038/s41598-019-45626-w. Sci Rep. 2019. PMID: 31235749 Free PMC article.
Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor.
Lee J, Kim JH, Biter AB, Sielaff B, Lee S, Tsai FT. Lee J, et al. Among authors: sielaff b. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8513-8. doi: 10.1073/pnas.1217988110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650362 Free PMC article.
30 results