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Amyloid-ß-directed immunotherapy for Alzheimer's disease.
Lannfelt L, Relkin NR, Siemers ER. Lannfelt L, et al. Among authors: siemers er. J Intern Med. 2014 Mar;275(3):284-95. doi: 10.1111/joim.12168. J Intern Med. 2014. PMID: 24605809 Free PMC article. Review.
Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease.
Portelius E, Zetterberg H, Dean RA, Marcil A, Bourgeois P, Nutu M, Andreasson U, Siemers E, Mawuenyega KG, Sigurdson WC, May PC, Paul SM, Holtzman DM, Blennow K, Bateman RJ. Portelius E, et al. J Alzheimers Dis. 2012;31(2):335-41. doi: 10.3233/JAD-2012-120508. J Alzheimers Dis. 2012. PMID: 22531418 Free PMC article. Clinical Trial.
Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.
Honig LS, Vellas B, Woodward M, Boada M, Bullock R, Borrie M, Hager K, Andreasen N, Scarpini E, Liu-Seifert H, Case M, Dean RA, Hake A, Sundell K, Poole Hoffmann V, Carlson C, Khanna R, Mintun M, DeMattos R, Selzler KJ, Siemers E. Honig LS, et al. N Engl J Med. 2018 Jan 25;378(4):321-330. doi: 10.1056/NEJMoa1705971. N Engl J Med. 2018. PMID: 29365294 Free article. Clinical Trial.
Improving Alzheimer's disease phase II clinical trials.
Greenberg BD, Carrillo MC, Ryan JM, Gold M, Gallagher K, Grundman M, Berman RM, Ashwood T, Siemers ER. Greenberg BD, et al. Among authors: siemers er. Alzheimers Dement. 2013 Jan;9(1):39-49. doi: 10.1016/j.jalz.2012.02.002. Epub 2012 Nov 16. Alzheimers Dement. 2013. PMID: 23164548
Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease.
Carrillo MC, Brashear HR, Logovinsky V, Ryan JM, Feldman HH, Siemers ER, Abushakra S, Hartley DM, Petersen RC, Khachaturian AS, Sperling RA. Carrillo MC, et al. Among authors: siemers er. Alzheimers Dement. 2013 Mar;9(2):123-131.e1. doi: 10.1016/j.jalz.2012.12.004. Epub 2013 Feb 12. Alzheimers Dement. 2013. PMID: 23411394 Review.
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R; Contributors. Jack CR Jr, et al. Alzheimers Dement. 2018 Apr;14(4):535-562. doi: 10.1016/j.jalz.2018.02.018. Alzheimers Dement. 2018. PMID: 29653606 Free PMC article. Review.
The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable.
Knopman DS, Haeberlein SB, Carrillo MC, Hendrix JA, Kerchner G, Margolin R, Maruff P, Miller DS, Tong G, Tome MB, Murray ME, Nelson PT, Sano M, Mattsson N, Sultzer DL, Montine TJ, Jack CR Jr, Kolb H, Petersen RC, Vemuri P, Canniere MZ, Schneider JA, Resnick SM, Romano G, van Harten AC, Wolk DA, Bain LJ, Siemers E. Knopman DS, et al. Alzheimers Dement. 2018 Apr;14(4):563-575. doi: 10.1016/j.jalz.2018.03.002. Alzheimers Dement. 2018. PMID: 29653607 Free PMC article. Review.
148 results