Sigel E - Search Results

1

The benzodiazepine binding site of GABAA receptors.

Sigel E, Buhr A. Sigel E, et al. Trends Pharmacol Sci. 1997 Nov;18(11):425-9. doi: 10.1016/s0165-6147(97)01118-8. Trends Pharmacol Sci. 1997. PMID: 9426470 Review.

2

TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes.

Steinmann ME, Schmidt RS, Bütikofer P, Mäser P, Sigel E. Steinmann ME, et al. Among authors: sigel e. Sci Rep. 2017 Apr 6;7(1):656. doi: 10.1038/s41598-017-00752-1. Sci Rep. 2017. PMID: 28386071 Free PMC article.

3

Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors.

Fedurco M, Gregorová J, Šebrlová K, Kantorová J, Peš O, Baur R, Sigel E, Táborská E. Fedurco M, et al. Among authors: sigel e. Biochem Res Int. 2015;2015:617620. doi: 10.1155/2015/617620. Epub 2015 Oct 5. Biochem Res Int. 2015. PMID: 26509084 Free PMC article.

4

Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital.

Maldifassi MC, Baur R, Sigel E. Maldifassi MC, et al. Among authors: sigel e. Neuropharmacology. 2016 Jun;105:207-214. doi: 10.1016/j.neuropharm.2016.01.003. Epub 2016 Jan 6. Neuropharmacology. 2016. PMID: 26767954

5

Accelerated discovery of novel benzodiazepine ligands by experiment-guided virtual screening.

Middendorp SJ, Puthenkalam R, Baur R, Ernst M, Sigel E. Middendorp SJ, et al. Among authors: sigel e. ACS Chem Biol. 2014 Aug 15;9(8):1854-9. doi: 10.1021/cb5001873. Epub 2014 Jun 27. ACS Chem Biol. 2014. PMID: 24960548

6

Anticipating antiport in P-type ATPases.

Niggli V, Sigel E. Niggli V, et al. Among authors: sigel e. Trends Biochem Sci. 2008 Apr;33(4):156-60. doi: 10.1016/j.tibs.2007.12.005. Epub 2008 Mar 17. Trends Biochem Sci. 2008. PMID: 18343670

7

Use of concatamers to study GABAA receptor architecture and function: application to delta-subunit-containing receptors and possible pitfalls.

Sigel E, Kaur KH, Lüscher BP, Baur R. Sigel E, et al. Biochem Soc Trans. 2009 Dec;37(Pt 6):1338-42. doi: 10.1042/BST0371338. Biochem Soc Trans. 2009. PMID: 19909272

8

Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors.

Wongsamitkul N, Baur R, Sigel E. Wongsamitkul N, et al. Among authors: sigel e. J Biol Chem. 2016 Aug 26;291(35):18474-83. doi: 10.1074/jbc.M116.738906. Epub 2016 Jul 5. J Biol Chem. 2016. PMID: 27382064 Free PMC article.

9

Structure, function, and modulation of GABA(A) receptors.

Sigel E, Steinmann ME. Sigel E, et al. J Biol Chem. 2012 Nov 23;287(48):40224-31. doi: 10.1074/jbc.R112.386664. Epub 2012 Oct 4. J Biol Chem. 2012. PMID: 23038269 Free PMC article. Review.

10

Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs.

Baur R, Tan KR, Lüscher BP, Gonthier A, Goeldner M, Sigel E. Baur R, et al. Among authors: sigel e. J Neurochem. 2008 Sep;106(6):2353-63. doi: 10.1111/j.1471-4159.2008.05574.x. Epub 2008 Jul 15. J Neurochem. 2008. PMID: 18643789

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