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104 results
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Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial.
Vrijlandt EJLE, El Azzi G, Vandewalker M, Rupp N, Harper T, Graham L, Szefler SJ, Moroni-Zentgraf P, Sharma A, Vulcu SD, Sigmund R, Chawes B, Engel M, Bisgaard H. Vrijlandt EJLE, et al. Among authors: sigmund r. Lancet Respir Med. 2018 Feb;6(2):127-137. doi: 10.1016/S2213-2600(18)30012-2. Epub 2018 Jan 18. Lancet Respir Med. 2018. PMID: 29361462 Clinical Trial.
Tiotropium in asthma poorly controlled with standard combination therapy.
Kerstjens HA, Engel M, Dahl R, Paggiaro P, Beck E, Vandewalker M, Sigmund R, Seibold W, Moroni-Zentgraf P, Bateman ED. Kerstjens HA, et al. Among authors: sigmund r. N Engl J Med. 2012 Sep 27;367(13):1198-207. doi: 10.1056/NEJMoa1208606. Epub 2012 Sep 2. N Engl J Med. 2012. PMID: 22938706 Clinical Trial.
Tiotropium add-on therapy improves lung function in children with symptomatic moderate asthma.
Vogelberg C, Engel M, Laki I, Bernstein JA, Schmidt O, El Azzi G, Moroni-Zentgraf P, Sigmund R, Hamelmann E. Vogelberg C, et al. Among authors: sigmund r. J Allergy Clin Immunol Pract. 2018 Nov-Dec;6(6):2160-2162.e9. doi: 10.1016/j.jaip.2018.04.032. Epub 2018 May 8. J Allergy Clin Immunol Pract. 2018. PMID: 29751157 Clinical Trial. No abstract available.
Clinical trial of a leucotriene B4 receptor antagonist, BIIL 284, in patients with rheumatoid arthritis.
Díaz-González F, Alten RH, Bensen WG, Brown JP, Sibley JT, Dougados M, Bombardieri S, Durez P, Ortiz P, de-Miquel G, Staab A, Sigmund R, Salin L, Leledy C, Polmar SH. Díaz-González F, et al. Among authors: sigmund r. Ann Rheum Dis. 2007 May;66(5):628-32. doi: 10.1136/ard.2006.062554. Epub 2006 Dec 14. Ann Rheum Dis. 2007. PMID: 17170051 Free PMC article. Clinical Trial.
Pharmacodynamics and Pharmacokinetics Following Once-Daily and Twice-Daily Dosing of Tiotropium Respimat® in Asthma Using Standardized Sample-Contamination Avoidance.
Beeh KM, Kirsten AM, Dusser D, Sharma A, Cornelissen P, Sigmund R, Moroni-Zentgraf P, Dahl R. Beeh KM, et al. Among authors: sigmund r. J Aerosol Med Pulm Drug Deliv. 2016 Oct;29(5):406-415. doi: 10.1089/jamp.2015.1260. Epub 2016 Feb 9. J Aerosol Med Pulm Drug Deliv. 2016. PMID: 26859538 Free PMC article.
104 results