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IRX-2, a novel in vivo immunotherapeutic, induces maturation and activation of human dendritic cells in vitro.
Egan JE, Quadrini KJ, Santiago-Schwarz F, Hadden JW, Brandwein HJ, Signorelli KL. Egan JE, et al. Among authors: signorelli kl. J Immunother. 2007 Sep;30(6):624-33. doi: 10.1097/CJI.0b013e3180691593. J Immunother. 2007. PMID: 17667526
IRX-2, a novel immunotherapeutic, protects human T cells from tumor-induced cell death.
Czystowska M, Han J, Szczepanski MJ, Szajnik M, Quadrini K, Brandwein H, Hadden JW, Signorelli K, Whiteside TL. Czystowska M, et al. Cell Death Differ. 2009 May;16(5):708-18. doi: 10.1038/cdd.2008.197. Epub 2009 Jan 30. Cell Death Differ. 2009. PMID: 19180118 Free PMC article.
T cell immunostimulation by methyl inosine 5'-monophosphate: application to infectious diseases.
Signorelli KL, Hadden JW. Signorelli KL, et al. Int Immunopharmacol. 2003 Aug;3(8):1177-86. doi: 10.1016/S1567-5769(03)00010-9. Int Immunopharmacol. 2003. PMID: 12860173 Review.
Evaluation of methyl inosine monophosphate (MIMP) and peramivir activities in a murine model of lethal influenza A virus infection.
Mishin VP, Hayden FG, Signorelli KL, Gubareva LV. Mishin VP, et al. Among authors: signorelli kl. Antiviral Res. 2006 Aug;71(1):64-8. doi: 10.1016/j.antiviral.2006.02.006. Epub 2006 Mar 9. Antiviral Res. 2006. PMID: 16581141
The importance of DR4Dw4 beta chain residues 70, 71, and 86 in peptide binding and T cell recognition.
Signorelli KL, Watts LM, Lambert LE. Signorelli KL, et al. Cell Immunol. 1995 May;162(2):217-24. doi: 10.1006/cimm.1995.1072. Cell Immunol. 1995. PMID: 7743549