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117 results
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Structural biology: Life's transistors.
Sigworth FJ. Sigworth FJ. Nature. 2003 May 1;423(6935):21-2. doi: 10.1038/423021a. Nature. 2003. PMID: 12721605 No abstract available.
Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy.
Wang L, Sigworth FJ. Wang L, et al. Among authors: sigworth fj. Nature. 2009 Sep 10;461(7261):292-5. doi: 10.1038/nature08291. Epub 2009 Aug 30. Nature. 2009. PMID: 19718020 Free PMC article.
Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
Brown MR, Kronengold J, Gazula VR, Chen Y, Strumbos JG, Sigworth FJ, Navaratnam D, Kaczmarek LK. Brown MR, et al. Among authors: sigworth fj. Nat Neurosci. 2010 Jul;13(7):819-21. doi: 10.1038/nn.2563. Epub 2010 May 30. Nat Neurosci. 2010. PMID: 20512134 Free PMC article.
From cryo-EM, multiple protein structures in one shot.
Sigworth FJ. Sigworth FJ. Nat Methods. 2007 Jan;4(1):20-1. doi: 10.1038/nmeth0107-20. Nat Methods. 2007. PMID: 17195021 No abstract available.
State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels.
Miranda P, Contreras JE, Plested AJ, Sigworth FJ, Holmgren M, Giraldez T. Miranda P, et al. Among authors: sigworth fj. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5217-22. doi: 10.1073/pnas.1219611110. Epub 2013 Mar 11. Proc Natl Acad Sci U S A. 2013. PMID: 23479636 Free PMC article.
Current carried by the Slc26 family member prestin does not flow through the transporter pathway.
Bai JP, Moeini-Naghani I, Zhong S, Li FY, Bian S, Sigworth FJ, Santos-Sacchi J, Navaratnam D. Bai JP, et al. Among authors: sigworth fj. Sci Rep. 2017 Apr 19;7:46619. doi: 10.1038/srep46619. Sci Rep. 2017. PMID: 28422190 Free PMC article.
The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels.
Chen H, Kronengold J, Yan Y, Gazula VR, Brown MR, Ma L, Ferreira G, Yang Y, Bhattacharjee A, Sigworth FJ, Salkoff L, Kaczmarek LK. Chen H, et al. Among authors: sigworth fj. J Neurosci. 2009 Apr 29;29(17):5654-65. doi: 10.1523/JNEUROSCI.5978-08.2009. J Neurosci. 2009. PMID: 19403831 Free PMC article.
Spherical reconstruction: a method for structure determination of membrane proteins from cryo-EM images.
Jiang QX, Chester DW, Sigworth FJ. Jiang QX, et al. Among authors: sigworth fj. J Struct Biol. 2001 Feb-Mar;133(2-3):119-31. doi: 10.1006/jsbi.2001.4376. J Struct Biol. 2001. PMID: 11472084
Gramicidin channel controversy--the structure in a lipid environment.
Andersen OS, Apell HJ, Bamberg E, Busath DD, Koeppe RE 2nd, Sigworth FJ, Szabo G, Urry DW, Woolley A. Andersen OS, et al. Among authors: sigworth fj. Nat Struct Biol. 1999 Jul;6(7):609; discussion 611-2. doi: 10.1038/10648. Nat Struct Biol. 1999. PMID: 10404209 No abstract available.
A maximum-likelihood approach to single-particle image refinement.
Sigworth FJ. Sigworth FJ. J Struct Biol. 1998;122(3):328-39. doi: 10.1006/jsbi.1998.4014. J Struct Biol. 1998. PMID: 9774537
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