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Year Number of Results
2013 1
2016 3
2017 3
2018 3
2019 3
2020 1
2021 3
2022 3
2023 6
2024 2

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27 results

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Page 1
ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing.
Clemente P, Calvo-Garrido J, Pearce SF, Schober FA, Shigematsu M, Siira SJ, Laine I, Spåhr H, Steinmetzger C, Petzold K, Kirino Y, Wibom R, Rackham O, Filipovska A, Rorbach J, Freyer C, Wredenberg A. Clemente P, et al. Among authors: siira sj. Nat Commun. 2022 Sep 30;13(1):5750. doi: 10.1038/s41467-022-33368-9. Nat Commun. 2022. PMID: 36180430 Free PMC article.
Computationally designed hyperactive Cas9 enzymes.
Vos PD, Rossetti G, Mantegna JL, Siira SJ, Gandadireja AP, Bruce M, Raven SA, Khersonsky O, Fleishman SJ, Filipovska A, Rackham O. Vos PD, et al. Among authors: siira sj. Nat Commun. 2022 May 31;13(1):3023. doi: 10.1038/s41467-022-30598-9. Nat Commun. 2022. PMID: 35641498 Free PMC article.
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication.
Jiang M, Xie X, Zhu X, Jiang S, Milenkovic D, Misic J, Shi Y, Tandukar N, Li X, Atanassov I, Jenninger L, Hoberg E, Albarran-Gutierrez S, Szilagyi Z, Macao B, Siira SJ, Carelli V, Griffith JD, Gustafsson CM, Nicholls TJ, Filipovska A, Larsson NG, Falkenberg M. Jiang M, et al. Among authors: siira sj. Sci Adv. 2021 Jul 2;7(27):eabf8631. doi: 10.1126/sciadv.abf8631. Print 2021 Jul. Sci Adv. 2021. PMID: 34215584 Free PMC article.
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion.
Misic J, Milenkovic D, Al-Behadili A, Xie X, Jiang M, Jiang S, Filograna R, Koolmeister C, Siira SJ, Jenninger L, Filipovska A, Clausen AR, Caporali L, Valentino ML, La Morgia C, Carelli V, Nicholls TJ, Wredenberg A, Falkenberg M, Larsson NG. Misic J, et al. Among authors: siira sj. Nucleic Acids Res. 2022 Aug 26;50(15):8749-8766. doi: 10.1093/nar/gkac661. Nucleic Acids Res. 2022. PMID: 35947649 Free PMC article.
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network.
Lee RG, Rudler DL, Raven SA, Peng L, Chopin A, Moh ESX, McCubbin T, Siira SJ, Fagan SV, DeBono NJ, Stentenbach M, Browne J, Rackham FF, Li J, Simpson KJ, Marcellin E, Packer NH, Reid GE, Padman BS, Rackham O, Filipovska A. Lee RG, et al. Among authors: siira sj. Nat Cell Biol. 2024 Jan;26(1):57-71. doi: 10.1038/s41556-023-01297-4. Epub 2023 Dec 21. Nat Cell Biol. 2024. PMID: 38129691
LRPPRC-mediated folding of the mitochondrial transcriptome.
Siira SJ, Spåhr H, Shearwood AJ, Ruzzenente B, Larsson NG, Rackham O, Filipovska A. Siira SJ, et al. Nat Commun. 2017 Nov 16;8(1):1532. doi: 10.1038/s41467-017-01221-z. Nat Commun. 2017. PMID: 29146908 Free PMC article.
27 results