Silanskas A - Search Results

1

PAM recognition by miniature CRISPR-Cas12f nucleases triggers programmable double-stranded DNA target cleavage.

Karvelis T, Bigelyte G, Young JK, Hou Z, Zedaveinyte R, Budre K, Paulraj S, Djukanovic V, Gasior S, Silanskas A, Venclovas Č, Siksnys V. Karvelis T, et al. Among authors: silanskas a. Nucleic Acids Res. 2020 May 21;48(9):5016-5023. doi: 10.1093/nar/gkaa208. Nucleic Acids Res. 2020. PMID: 32246713 Free PMC article.

2

Photocaged variants of the MunI and PvuII restriction enzymes.

Silanskas A, Foss M, Wende W, Urbanke C, Lagunavicius A, Pingoud A, Siksnys V. Silanskas A, et al. Biochemistry. 2011 Apr 12;50(14):2800-7. doi: 10.1021/bi2000609. Epub 2011 Mar 16. Biochemistry. 2011. PMID: 21410225

3

Catalytic activity control of restriction endonuclease--triplex forming oligonucleotide conjugates.

Silanskas A, Zaremba M, Sasnauskas G, Siksnys V. Silanskas A, et al. Bioconjug Chem. 2012 Feb 15;23(2):203-11. doi: 10.1021/bc200480m. Epub 2012 Jan 30. Bioconjug Chem. 2012. PMID: 22236287

4

DNA cleavage by CgII and NgoAVII requires interaction between N- and R-proteins and extensive nucleotide hydrolysis.

Zaremba M, Toliusis P, Grigaitis R, Manakova E, Silanskas A, Tamulaitiene G, Szczelkun MD, Siksnys V. Zaremba M, et al. Among authors: silanskas a. Nucleic Acids Res. 2014 Dec 16;42(22):13887-96. doi: 10.1093/nar/gku1236. Epub 2014 Nov 27. Nucleic Acids Res. 2014. PMID: 25429977 Free PMC article.

5

Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.

Tamulaitiene G, Silanskas A, Grazulis S, Zaremba M, Siksnys V. Tamulaitiene G, et al. Among authors: silanskas a. Nucleic Acids Res. 2014 Dec 16;42(22):14022-30. doi: 10.1093/nar/gku1237. Epub 2014 Nov 27. Nucleic Acids Res. 2014. PMID: 25429979 Free PMC article.

6

DNA cleavage by CgII and NgoAVII requires interaction between N- and R-proteins and extensive nucleotide hydrolysis.

Zaremba M, Toliusis P, Grigaitis R, Manakova E, Silanskas A, Tamulaitiene G, Szczelkun MD, Siksnys V, Tamulaitiene G, Silanskas A, Grazulis S, Zaremba M, Siksnys V. Zaremba M, et al. Among authors: silanskas a. Nucleic Acids Res. 2015 Mar 31;43(6):3405. doi: 10.1093/nar/gkv049. Epub 2015 Mar 13. Nucleic Acids Res. 2015. PMID: 25769528 Free PMC article. No abstract available.

7

Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements.

Karvelis T, Gasiunas G, Young J, Bigelyte G, Silanskas A, Cigan M, Siksnys V. Karvelis T, et al. Among authors: silanskas a. Genome Biol. 2015 Nov 19;16:253. doi: 10.1186/s13059-015-0818-7. Genome Biol. 2015. PMID: 26585795 Free PMC article.

8

CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases.

Toliusis P, Zaremba M, Silanskas A, Szczelkun MD, Siksnys V. Toliusis P, et al. Among authors: silanskas a. Nucleic Acids Res. 2017 Aug 21;45(14):8435-8447. doi: 10.1093/nar/gkx580. Nucleic Acids Res. 2017. PMID: 28854738 Free PMC article.

9

The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor.

Toliusis P, Tamulaitiene G, Grigaitis R, Tuminauskaite D, Silanskas A, Manakova E, Venclovas C, Szczelkun MD, Siksnys V, Zaremba M. Toliusis P, et al. Among authors: silanskas a. Nucleic Acids Res. 2018 Mar 16;46(5):2560-2572. doi: 10.1093/nar/gky107. Nucleic Acids Res. 2018. PMID: 29471489 Free PMC article.

10

DnaQ exonuclease-like domain of Cas2 promotes spacer integration in a type I-E CRISPR-Cas system.

Drabavicius G, Sinkunas T, Silanskas A, Gasiunas G, Venclovas Č, Siksnys V. Drabavicius G, et al. Among authors: silanskas a. EMBO Rep. 2018 Jul;19(7):e45543. doi: 10.15252/embr.201745543. Epub 2018 Jun 11. EMBO Rep. 2018. PMID: 29891635 Free PMC article.

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