Siler SQ - Search Results

1

The inhibition of gluconeogenesis following alcohol in humans.

Siler SQ, Neese RA, Christiansen MP, Hellerstein MK. Siler SQ, et al. Am J Physiol. 1998 Nov;275(5):E897-907. doi: 10.1152/ajpendo.1998.275.5.E897. Am J Physiol. 1998. PMID: 9815011 Clinical Trial.

2

VLDL-triglyceride production after alcohol ingestion, studied using [2-13C1] glycerol.

Siler SQ, Neese RA, Parks EJ, Hellerstein MK. Siler SQ, et al. J Lipid Res. 1998 Dec;39(12):2319-28. J Lipid Res. 1998. PMID: 9831620 Free article.

3

De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption.

Siler SQ, Neese RA, Hellerstein MK. Siler SQ, et al. Am J Clin Nutr. 1999 Nov;70(5):928-36. doi: 10.1093/ajcn/70.5.928. Am J Clin Nutr. 1999. PMID: 10539756 Clinical Trial.

4

Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation.

Neese RA, Siler SQ, Cesar D, Antelo F, Lee D, Misell L, Patel K, Tehrani S, Shah P, Hellerstein MK. Neese RA, et al. Among authors: siler sq. Anal Biochem. 2001 Nov 15;298(2):189-95. doi: 10.1006/abio.2001.5375. Anal Biochem. 2001. PMID: 11700973

5

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans.

Hellerstein M, Hanley MB, Cesar D, Siler S, Papageorgopoulos C, Wieder E, Schmidt D, Hoh R, Neese R, Macallan D, Deeks S, McCune JM. Hellerstein M, et al. Nat Med. 1999 Jan;5(1):83-9. doi: 10.1038/4772. Nat Med. 1999. PMID: 9883844

6

Factors influencing T-cell turnover in HIV-1-seropositive patients.

McCune JM, Hanley MB, Cesar D, Halvorsen R, Hoh R, Schmidt D, Wieder E, Deeks S, Siler S, Neese R, Hellerstein M. McCune JM, et al. J Clin Invest. 2000 Mar;105(5):R1-8. doi: 10.1172/JCI8647. J Clin Invest. 2000. PMID: 10712441 Free PMC article.

7

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury.

Beaudoin JJ, Clemens L, Miedel MT, Gough A, Zaidi F, Ramamoorthy P, Wong KE, Sarangarajan R, Battista C, Shoda LKM, Siler SQ, Taylor DL, Howell BA, Vernetti LA, Yang K. Beaudoin JJ, et al. Among authors: siler sq. Int J Mol Sci. 2023 Jun 2;24(11):9692. doi: 10.3390/ijms24119692. Int J Mol Sci. 2023. PMID: 37298645 Free PMC article.

8

Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition.

Beaudoin JJ, Yang K, Adiwidjaja J, Taneja G, Watkins PB, Siler SQ, Howell BA, Woodhead JL. Beaudoin JJ, et al. Among authors: siler sq. Front Pharmacol. 2023 Jan 17;13:1085621. doi: 10.3389/fphar.2022.1085621. eCollection 2022. Front Pharmacol. 2023. PMID: 36733378 Free PMC article.

9

Applications of Quantitative Systems Pharmacology (QSP) in Drug Development for NAFLD and NASH and Its Regulatory Application.

Siler SQ. Siler SQ. Pharm Res. 2022 Aug;39(8):1789-1802. doi: 10.1007/s11095-022-03295-x. Epub 2022 May 24. Pharm Res. 2022. PMID: 35610402 Free PMC article.

10

Comparing the Liver Safety Profiles of 4 Next-Generation CGRP Receptor Antagonists to the Hepatotoxic CGRP Inhibitor Telcagepant Using Quantitative Systems Toxicology Modeling.

Woodhead JL, Siler SQ, Howell BA, Watkins PB, Conway C. Woodhead JL, et al. Among authors: siler sq. Toxicol Sci. 2022 Jun 28;188(1):108-116. doi: 10.1093/toxsci/kfac051. Toxicol Sci. 2022. PMID: 35556143 Free PMC article.

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