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Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.
Dash PK, Kaminski R, Bella R, Su H, Mathews S, Ahooyi TM, Chen C, Mancuso P, Sariyer R, Ferrante P, Donadoni M, Robinson JA, Sillman B, Lin Z, Hilaire JR, Banoub M, Elango M, Gautam N, Mosley RL, Poluektova LY, McMillan J, Bade AN, Gorantla S, Sariyer IK, Burdo TH, Young WB, Amini S, Gordon J, Jacobson JM, Edagwa B, Khalili K, Gendelman HE. Dash PK, et al. Among authors: sillman b. Nat Commun. 2019 Jul 2;10(1):2753. doi: 10.1038/s41467-019-10366-y. Nat Commun. 2019. PMID: 31266936 Free PMC article.
Long-acting slow effective release antiretroviral therapy.
Edagwa B, McMillan J, Sillman B, Gendelman HE. Edagwa B, et al. Among authors: sillman b. Expert Opin Drug Deliv. 2017 Nov;14(11):1281-1291. doi: 10.1080/17425247.2017.1288212. Epub 2017 Feb 6. Expert Opin Drug Deliv. 2017. PMID: 28128004 Free PMC article. Review.
Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques.
McMillan J, Szlachetka A, Slack L, Sillman B, Lamberty B, Morsey B, Callen S, Gautam N, Alnouti Y, Edagwa B, Gendelman HE, Fox HS. McMillan J, et al. Among authors: sillman b. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01316-17. doi: 10.1128/AAC.01316-17. Print 2018 Jan. Antimicrob Agents Chemother. 2017. PMID: 29061742 Free PMC article.
Creation of a long-acting nanoformulated dolutegravir.
Sillman B, Bade AN, Dash PK, Bhargavan B, Kocher T, Mathews S, Su H, Kanmogne GD, Poluektova LY, Gorantla S, McMillan J, Gautam N, Alnouti Y, Edagwa B, Gendelman HE. Sillman B, et al. Nat Commun. 2018 Feb 6;9(1):443. doi: 10.1038/s41467-018-02885-x. Nat Commun. 2018. PMID: 29402886 Free PMC article.
Creation of a long-acting rilpivirine prodrug nanoformulation.
Hilaire JR, Bade AN, Sillman B, Gautam N, Herskovitz J, Dyavar Shetty BL, Wojtkiewicz MS, Szlachetka A, Lamberty BG, Sravanam S, Fox HS, Alnouti Y, Dash PK, McMillan JM, Edagwa BJ, Gendelman HE. Hilaire JR, et al. Among authors: sillman b. J Control Release. 2019 Oct;311-312:201-211. doi: 10.1016/j.jconrel.2019.09.001. Epub 2019 Sep 3. J Control Release. 2019. PMID: 31491432 Free PMC article.
A year-long extended release nanoformulated cabotegravir prodrug.
Kulkarni TA, Bade AN, Sillman B, Shetty BLD, Wojtkiewicz MS, Gautam N, Hilaire JR, Sravanam S, Szlachetka A, Lamberty BG, Morsey BM, Fox HS, Alnouti Y, McMillan JM, Mosley RL, Meza J, Domanico PL, Yue TY, Moore G, Edagwa BJ, Gendelman HE. Kulkarni TA, et al. Among authors: sillman b. Nat Mater. 2020 Aug;19(8):910-920. doi: 10.1038/s41563-020-0674-z. Epub 2020 Apr 27. Nat Mater. 2020. PMID: 32341511 Free PMC article.
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