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Extreme hyperopia is the result of null mutations in MFRP, which encodes a Frizzled-related protein.
Sundin OH, Leppert GS, Silva ED, Yang JM, Dharmaraj S, Maumenee IH, Santos LC, Parsa CF, Traboulsi EI, Broman KW, Dibernardo C, Sunness JS, Toy J, Weinberg EM. Sundin OH, et al. Among authors: silva ed. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9553-8. doi: 10.1073/pnas.0501451102. Epub 2005 Jun 23. Proc Natl Acad Sci U S A. 2005. PMID: 15976030 Free PMC article.
Structure-based design, optimization of lead, synthesis, and biological evaluation of compounds active against Trypanosoma cruzi.
de Almeida GC, de Oliveira GB, da Silva Monte Z, Costa ÉCS, da Silva Falcão EP, Scotti L, Scotti MT, Oliveira Silva R, Pereira VRA, da Silva ED, Junior PAS, de Andrade Cavalcante MK, de Melo SJ. de Almeida GC, et al. Among authors: da silva ed. Chem Biol Drug Des. 2023 Oct;102(4):843-856. doi: 10.1111/cbdd.14294. Epub 2023 Jul 16. Chem Biol Drug Des. 2023. PMID: 37455325
252 results