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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
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1970 1
1971 1
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1976 1
1977 3
1978 1
1979 2
1980 1
1981 1
1982 2
1984 2
1985 1
1988 2
1989 4
1990 1
1991 5
1992 1
1995 5
1996 2
1998 8
1999 13
2000 11
2001 17
2002 24
2003 26
2004 25
2005 36
2006 29
2007 56
2008 41
2009 48
2010 54
2011 54
2012 58
2013 88
2014 75
2015 76
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2018 80
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1,498 results

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Page 1
Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases.
Abenavoli L, Izzo AA, Milić N, Cicala C, Santini A, Capasso R. Abenavoli L, et al. Phytother Res. 2018 Nov;32(11):2202-2213. doi: 10.1002/ptr.6171. Epub 2018 Aug 6. Phytother Res. 2018. PMID: 30080294 Review.
Milk thistle (MT; Silybum marianum), a member of the Asteraceae family, is a therapeutic herb with a 2,000-year history of use. ...
Milk thistle (MT; Silybum marianum), a member of the Asteraceae family, is a therapeutic herb with a 2,000-year history of use …
Silybum marianum: An Overview of its Phytochemistry and Pharmacological Activities with Emphasis on Potential Anticancer Properties.
Nawaz A, Zaib S, Khan I, Ahmed A, Shahzadi K, Riaz H. Nawaz A, et al. Anticancer Agents Med Chem. 2023;23(13):1519-1534. doi: 10.2174/1871520623666230412111152. Anticancer Agents Med Chem. 2023. PMID: 37055902 Review.
Silybum marianum (SM) belongs to the family Asteraceae, which holds therapeutic significance in medicinal chemistry. ...
Silybum marianum (SM) belongs to the family Asteraceae, which holds therapeutic significance in medicinal chemistry. ...
Health Benefits of Silybum marianum: Phytochemistry, Pharmacology, and Applications.
Wang X, Zhang Z, Wu SC. Wang X, et al. J Agric Food Chem. 2020 Oct 21;68(42):11644-11664. doi: 10.1021/acs.jafc.0c04791. Epub 2020 Oct 12. J Agric Food Chem. 2020. PMID: 33045827 Review.
Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been widely used to treat various diseases, especially hepatic diseases. ...
Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been widely used to treat various diseases, …
Silybum marianum (milk thistle) and its main constituent, silymarin, as a potential therapeutic plant in metabolic syndrome: A review.
Tajmohammadi A, Razavi BM, Hosseinzadeh H. Tajmohammadi A, et al. Phytother Res. 2018 Oct;32(10):1933-1949. doi: 10.1002/ptr.6153. Epub 2018 Jul 17. Phytother Res. 2018. PMID: 30015401 Review.
Herbal therapy plays an important role for treatment of different diseases. Silybum marianum is a plant that is used for centuries as a herbal treatment in liver and biliary tract diseases. Silymarin is the main component of S. marianum and derived from fruit …
Herbal therapy plays an important role for treatment of different diseases. Silybum marianum is a plant that is used for centu …
The food plant Silybum marianum (L.) Gaertn.: Phytochemistry, Ethnopharmacology and clinical evidence.
Marmouzi I, Bouyahya A, Ezzat SM, El Jemli M, Kharbach M. Marmouzi I, et al. J Ethnopharmacol. 2021 Jan 30;265:113303. doi: 10.1016/j.jep.2020.113303. Epub 2020 Sep 1. J Ethnopharmacol. 2021. PMID: 32877720 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Silybum marianum (L.) Gaertn. or Milk thistle is a medicinal plant native to Northern Africa, Southern Europe, Southern Russia and Anatolia. ...RESULTS: S. marianum was subjected to thousands of ethnopharmacological, experiment …
ETHNOPHARMACOLOGICAL RELEVANCE: Silybum marianum (L.) Gaertn. or Milk thistle is a medicinal plant native to Northern Africa, …
Efficacy and Mechanisms of Silybum Marianum, Silymarin, and Silibinin on Rheumatoid Arthritis and Osteoarthritis Symptoms: A Systematic Review.
Ghahfarrokhi SH, Heidari-Soureshjani S, Sherwin CMT, Azadegan-Dehkordi Z. Ghahfarrokhi SH, et al. Curr Rheumatol Rev. 2024;20(4):414-425. doi: 10.2174/0115733971266397231122080247. Curr Rheumatol Rev. 2024. PMID: 38314596
OBJECTIVE: The current systematic review investigated the mechanisms of Silybum marianum, silymarin, and silibinin on RA and OA symptoms. METHODS: The PRISMA 2020 statement was used for reporting Items in this systematic review. ...Although silymarin and silibinin h …
OBJECTIVE: The current systematic review investigated the mechanisms of Silybum marianum, silymarin, and silibinin on RA and O …
Milk thistle (Silybum Marianum) as an antidote or a protective agent against natural or chemical toxicities: a review.
Fanoudi S, Alavi MS, Karimi G, Hosseinzadeh H. Fanoudi S, et al. Drug Chem Toxicol. 2020 May;43(3):240-254. doi: 10.1080/01480545.2018.1485687. Epub 2018 Jul 22. Drug Chem Toxicol. 2020. PMID: 30033764 Review.
Recently, herbal medicine is considered as a biological and safe treatment for toxicities. Silybum marianum (milk thistle), belongs to the Asteraceae family, possesses different effects such as hepatoprotective, cardioprotective, neuroprotective, anti-inflammatory a …
Recently, herbal medicine is considered as a biological and safe treatment for toxicities. Silybum marianum (milk thistle), be …
Silybum marianum-Derived Compounds in Prostate Cancer: Mechanisms of Action and Translational Potential.
Randisi F, Modoni G, Riva M, Perletti G, Odorico D, Marras E, Gariboldi MB. Randisi F, et al. Int J Mol Sci. 2026 May 20;27(10):4605. doi: 10.3390/ijms27104605. Int J Mol Sci. 2026. PMID: 42196582 Free PMC article. Review.
In this context, natural compounds are attracting increasing interest as adjunctive or novel therapeutic agents. Among these, silymarin, a Silybum marianum-derived flavonolignan complex, has shown promising antineoplastic activity in preclinical PCa models. ...
In this context, natural compounds are attracting increasing interest as adjunctive or novel therapeutic agents. Among these, silymarin, a …
Mechanistic Insights into the Pharmacological Significance of Silymarin.
Wadhwa K, Pahwa R, Kumar M, Kumar S, Sharma PC, Singh G, Verma R, Mittal V, Singh I, Kaushik D, Jeandet P. Wadhwa K, et al. Molecules. 2022 Aug 21;27(16):5327. doi: 10.3390/molecules27165327. Molecules. 2022. PMID: 36014565 Free PMC article. Review.
Silymarin is a plant-derived mixture of polyphenolic flavonoids originating from the fruits and akenes of Silybum marianum and contains three flavonolignans, silibinins (silybins), silychristin and silydianin, along with taxifolin. ...
Silymarin is a plant-derived mixture of polyphenolic flavonoids originating from the fruits and akenes of Silybum marianum and …
1,498 results