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24 results

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Page 1
[18F]SF51, a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in brain, works well in monkeys but fails in humans.
Yan X, Siméon FG, Liow JS, Morse CL, Jana S, Montero Santamaria JA, Jenkins M, Zoghbi SS, Pike VW, Innis RB, Zanotti-Fregonara P. Yan X, et al. Among authors: simeon fg. J Cereb Blood Flow Metab. 2024 Dec 9:271678X241304924. doi: 10.1177/0271678X241304924. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39654356 Free PMC article.
Gas Phase Transformations in Carbon-11 Chemistry.
Lu S, Telu S, Siméon FG, Cai L, Pike VW. Lu S, et al. Among authors: simeon fg. Int J Mol Sci. 2024 Jan 18;25(2):1167. doi: 10.3390/ijms25021167. Int J Mol Sci. 2024. PMID: 38256240 Free PMC article. Review.
In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.
Yan X, Siméon FG, Liow JS, Morse CL, Montero Santamaria JA, Jenkins M, Manly LS, Van Buskirk M, Zoghbi SS, Pike VW, Innis RB, Zanotti-Fregonara P. Yan X, et al. Among authors: simeon fg. Eur J Nucl Med Mol Imaging. 2023 Aug;50(10):2962-2970. doi: 10.1007/s00259-023-06270-9. Epub 2023 May 30. Eur J Nucl Med Mol Imaging. 2023. PMID: 37249618 Free PMC article.
Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand.
Siméon FG, Lee JH, Morse CL, Stukes I, Zoghbi SS, Manly LS, Liow JS, Gladding RL, Dick RM, Yan X, Taliani S, Costa B, Martini C, Da Settimo F, Castellano S, Innis RB, Pike VW. Siméon FG, et al. J Med Chem. 2021 Nov 25;64(22):16731-16745. doi: 10.1021/acs.jmedchem.1c01562. Epub 2021 Nov 10. J Med Chem. 2021. PMID: 34756026 Free PMC article.
Differential Pharmacophore Definition of the cAMP Binding Sites of Neuritogenic cAMP Sensor-Rapgef2, Protein Kinase A, and Exchange Protein Activated by cAMP in Neuroendocrine Cells Using an Adenine-Based Scaffold.
Emery AC, Alvarez RA, Eiden MV, Xu W, Siméon FG, Eiden LE. Emery AC, et al. Among authors: simeon fg. ACS Chem Neurosci. 2017 Jul 19;8(7):1500-1509. doi: 10.1021/acschemneuro.6b00462. Epub 2017 Mar 27. ACS Chem Neurosci. 2017. PMID: 28290664
Comparison of two PET radioligands, [11C]FPEB and [11C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain.
Lohith TG, Tsujikawa T, Siméon FG, Veronese M, Zoghbi SS, Lyoo CH, Kimura Y, Morse CL, Pike VW, Fujita M, Innis RB. Lohith TG, et al. Among authors: simeon fg. J Cereb Blood Flow Metab. 2017 Jul;37(7):2458-2470. doi: 10.1177/0271678X16668891. Epub 2016 Jan 1. J Cereb Blood Flow Metab. 2017. PMID: 27629098 Free PMC article.
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