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15 results
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Targeting the histone orthography of cancer: drugs for writers, erasers and readers.
Simó-Riudalbas L, Esteller M. Simó-Riudalbas L, et al. Br J Pharmacol. 2015 Jun;172(11):2716-32. doi: 10.1111/bph.12844. Epub 2014 Sep 5. Br J Pharmacol. 2015. PMID: 25039449 Free PMC article. Review.
Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer.
Pérez-Salvia M, Simó-Riudalbas L, Llinàs-Arias P, Roa L, Setien F, Soler M, de Moura MC, Bradner JE, Gonzalez-Suarez E, Moutinho C, Esteller M. Pérez-Salvia M, et al. Among authors: simo riudalbas l. Oncotarget. 2017 May 29;8(31):51621-51629. doi: 10.18632/oncotarget.18255. eCollection 2017 Aug 1. Oncotarget. 2017. PMID: 28881673 Free PMC article.
KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.
Simó-Riudalbas L, Pérez-Salvia M, Setien F, Villanueva A, Moutinho C, Martínez-Cardús A, Moran S, Berdasco M, Gomez A, Vidal E, Soler M, Heyn H, Vaquero A, de la Torre C, Barceló-Batllori S, Vidal A, Roz L, Pastorino U, Szakszon K, Borck G, Moura CS, Carneiro F, Zondervan I, Savola S, Iwakawa R, Kohno T, Yokota J, Esteller M. Simó-Riudalbas L, et al. Cancer Res. 2015 Sep 15;75(18):3936-45. doi: 10.1158/0008-5472.CAN-14-3702. Epub 2015 Jul 24. Cancer Res. 2015. PMID: 26208904 Free article.
Barcelona Conference on Epigenetics and Cancer: 50 years of histone acetylation.
Perez-Salvia M, Simó-Riudalbas L, Ausió J, Esteller M. Perez-Salvia M, et al. Among authors: simo riudalbas l. Epigenetics. 2015;10(5):446-51. doi: 10.1080/15592294.2015.1039222. Epigenetics. 2015. PMID: 25942103 Free PMC article.
Cancer genomics identifies disrupted epigenetic genes.
Simó-Riudalbas L, Esteller M. Simó-Riudalbas L, et al. Hum Genet. 2014 Jun;133(6):713-25. doi: 10.1007/s00439-013-1373-5. Epub 2013 Oct 9. Hum Genet. 2014. PMID: 24104525 Review.
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, Ropero S, Kalluri R, Croce CM, Calin GA, Esteller M. Melo S, et al. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4394-9. doi: 10.1073/pnas.1014720108. Epub 2011 Feb 28. Proc Natl Acad Sci U S A. 2011. PMID: 21368194 Free PMC article.
DNMT3B gene amplification predicts resistance to DNA demethylating drugs.
Simó-Riudalbas L, Melo SA, Esteller M. Simó-Riudalbas L, et al. Genes Chromosomes Cancer. 2011 Jul;50(7):527-34. doi: 10.1002/gcc.20877. Epub 2011 Apr 11. Genes Chromosomes Cancer. 2011. PMID: 21484930
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis.
Anadón C, Guil S, Simó-Riudalbas L, Moutinho C, Setien F, Martínez-Cardús A, Moran S, Villanueva A, Calaf M, Vidal A, Lazo PA, Zondervan I, Savola S, Kohno T, Yokota J, Ribas de Pouplana L, Esteller M. Anadón C, et al. Among authors: simo riudalbas l. Oncogene. 2016 Aug 18;35(33):4407-13. doi: 10.1038/onc.2015.469. Epub 2015 Dec 7. Oncogene. 2016. PMID: 26640150 Free PMC article.
DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia.
Ferreira HJ, Heyn H, Vizoso M, Moutinho C, Vidal E, Gomez A, Martínez-Cardús A, Simó-Riudalbas L, Moran S, Jost E, Esteller M. Ferreira HJ, et al. Among authors: simo riudalbas l. Oncogene. 2016 Jun 9;35(23):3079-82. doi: 10.1038/onc.2015.359. Epub 2015 Oct 5. Oncogene. 2016. PMID: 26434589 Free PMC article.
Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis.
Rodriguez-Paredes M, Martinez de Paz A, Simó-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vázquez-Cedeira M, Lazo PA, Carneiro F, Moura CS, Vieira J, Teixeira MR, Esteller M. Rodriguez-Paredes M, et al. Oncogene. 2014 May 22;33(21):2807-13. doi: 10.1038/onc.2013.239. Epub 2013 Jun 17. Oncogene. 2014. PMID: 23770855 Free PMC article.
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