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A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer.
Pietanza MC, Litvak AM, Varghese AM, Krug LM, Fleisher M, Teitcher JB, Holodny AI, Sima CS, Woo KM, Ng KK, Won HH, Berger MF, Kris MG, Rudin CM. Pietanza MC, et al. Among authors: sima cs. Lung Cancer. 2016 Sep;99:23-30. doi: 10.1016/j.lungcan.2016.04.014. Epub 2016 Apr 26. Lung Cancer. 2016. PMID: 27565909 Free PMC article. Clinical Trial.
Variation of breast cancer risk among BRCA1/2 carriers.
Begg CB, Haile RW, Borg A, Malone KE, Concannon P, Thomas DC, Langholz B, Bernstein L, Olsen JH, Lynch CF, Anton-Culver H, Capanu M, Liang X, Hummer AJ, Sima C, Bernstein JL. Begg CB, et al. JAMA. 2008 Jan 9;299(2):194-201. doi: 10.1001/jama.2007.55-a. JAMA. 2008. PMID: 18182601 Free PMC article.
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