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27 results

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Page 1
A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma.
Birch JL, Strathdee K, Gilmour L, Vallatos A, McDonald L, Kouzeli A, Vasan R, Qaisi AH, Croft DR, Crighton D, Gill K, Gray CH, Konczal J, Mezna M, McArthur D, Schüttelkopf AW, McConnell P, Sime M, Holmes WM, Bower J, McKinnon HJ, Drysdale M, Olson MF, Chalmers AJ. Birch JL, et al. Among authors: sime m. Cancer Res. 2018 Nov 15;78(22):6509-6522. doi: 10.1158/0008-5472.CAN-18-1697. Epub 2018 Oct 2. Cancer Res. 2018. PMID: 30279244
Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.
Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, Croft DR, Drysdale MJ, Garnett MJ, Gill K, Gray C, Greenhalgh DA, Hall JAM, Konczal J, Lilla S, McArthur D, McConnell P, McDonald L, McGarry L, McKinnon H, McMenemy C, Mezna M, Morrice NA, Munro J, Naylor G, Rath N, Schüttelkopf AW, Sime M, Olson MF. Unbekandt M, et al. Among authors: sime m. Cancer Res. 2018 Apr 15;78(8):2096-2114. doi: 10.1158/0008-5472.CAN-17-2870. Epub 2018 Jan 30. Cancer Res. 2018. PMID: 29382705 Free PMC article.
A novel small-molecule MRCK inhibitor blocks cancer cell invasion.
Unbekandt M, Croft DR, Crighton D, Mezna M, McArthur D, McConnell P, Schüttelkopf AW, Belshaw S, Pannifer A, Sime M, Bower J, Drysdale M, Olson MF. Unbekandt M, et al. Among authors: sime m. Cell Commun Signal. 2014 Oct 5;12:54. doi: 10.1186/s12964-014-0054-x. Cell Commun Signal. 2014. PMID: 25288205 Free PMC article.
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist.
Sime M, Allan AC, Chapman P, Fieldhouse C, Giblin GM, Healy MP, Lambert MH, Leesnitzer LM, Lewis A, Merrihew RV, Rutter RA, Sasse R, Shearer BG, Willson TM, Xu RX, Virley DJ. Sime M, et al. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5568-72. doi: 10.1016/j.bmcl.2011.06.088. Epub 2011 Jun 29. Bioorg Med Chem Lett. 2011. PMID: 21798739
Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists.
Allan AC, Billinton A, Brown SH, Chowdhury A, Eatherton AJ, Fieldhouse C, Giblin GM, Goldsmith P, Hall A, Hurst DN, Naylor A, Rawlings DA, Sime M, Scoccitti T, Theobald PJ. Allan AC, et al. Among authors: sime m. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4343-8. doi: 10.1016/j.bmcl.2011.05.047. Epub 2011 May 23. Bioorg Med Chem Lett. 2011. PMID: 21676612
The Magnitude of Hypertension and Its Contributing Factors Among Patients Receiving Antiretroviral Therapy in Public Hospitals in Harar City, Eastern Ethiopia: A Cross-Sectional Study.
Dechasa M, Nigussie S, Jambo A, Sime ML, Tamire A, Kitessa M, Degefu N, Dereje J, Demeke H, Legese N. Dechasa M, et al. Among authors: sime ml. Integr Blood Press Control. 2023 Nov 11;16:81-93. doi: 10.2147/IBPC.S433907. eCollection 2023. Integr Blood Press Control. 2023. PMID: 38023690 Free PMC article.
Low dose or very low dose phenylephrine and cyclopentolate microdrops for retinopathy of prematurity eye examinations (The Little Eye Drop Study): a randomised controlled non-inferiority trial.
Kremer LJ, Medlicott N, Sime MJ, Broadbent R, Edmonds L, Berry MJ, Austin NC, Alsweiler JM, Reith DM. Kremer LJ, et al. Among authors: sime mj. Arch Dis Child Fetal Neonatal Ed. 2023 Jul;108(4):380-386. doi: 10.1136/archdischild-2022-324929. Epub 2023 Jan 2. Arch Dis Child Fetal Neonatal Ed. 2023. PMID: 36593111 Free PMC article. Clinical Trial.
27 results