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DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice.
MacKay H, Scott CA, Duryea JD, Baker MS, Laritsky E, Elson AE, Garland T Jr, Fiorotto ML, Chen R, Li Y, Coarfa C, Simerly RB, Waterland RA. MacKay H, et al. Among authors: simerly rb. Nat Commun. 2019 Dec 2;10(1):5364. doi: 10.1038/s41467-019-13339-3. Nat Commun. 2019. PMID: 31792207 Free PMC article.
Developmental specification of metabolic circuitry.
Elson AE, Simerly RB. Elson AE, et al. Among authors: simerly rb. Front Neuroendocrinol. 2015 Oct;39:38-51. doi: 10.1016/j.yfrne.2015.09.003. Epub 2015 Sep 25. Front Neuroendocrinol. 2015. PMID: 26407637 Free PMC article. Review.
MC3R links nutritional state to childhood growth and the timing of puberty.
Lam BYH, Williamson A, Finer S, Day FR, Tadross JA, Gonçalves Soares A, Wade K, Sweeney P, Bedenbaugh MN, Porter DT, Melvin A, Ellacott KLJ, Lippert RN, Buller S, Rosmaninho-Salgado J, Dowsett GKC, Ridley KE, Xu Z, Cimino I, Rimmington D, Rainbow K, Duckett K, Holmqvist S, Khan A, Dai X, Bochukova EG; Genes & Health Research Team; Trembath RC, Martin HC, Coll AP, Rowitch DH, Wareham NJ, van Heel DA, Timpson N, Simerly RB, Ong KK, Cone RD, Langenberg C, Perry JRB, Yeo GS, O'Rahilly S. Lam BYH, et al. Among authors: simerly rb. Nature. 2021 Nov;599(7885):436-441. doi: 10.1038/s41586-021-04088-9. Epub 2021 Nov 3. Nature. 2021. PMID: 34732894 Free PMC article.
The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia.
Sweeney P, Bedenbaugh MN, Maldonado J, Pan P, Fowler K, Williams SY, Gimenez LE, Ghamari-Langroudi M, Downing G, Gui Y, Hadley CK, Joy ST, Mapp AK, Simerly RB, Cone RD. Sweeney P, et al. Among authors: simerly rb. Sci Transl Med. 2021 Apr 21;13(590):eabd6434. doi: 10.1126/scitranslmed.abd6434. Sci Transl Med. 2021. PMID: 33883274 Free PMC article.
Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.
van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE, Keogh JM, Riley SE, Papadia S, Henning E, Bounds R, Bochukova EG, Mistry V, O'Rahilly S, Simerly RB; INTERVAL; UK10K Consortium; Minchin JEN, Barroso I, Jones EY, Bouret SG, Farooqi IS. van der Klaauw AA, et al. Among authors: simerly rb. Cell. 2019 Feb 7;176(4):729-742.e18. doi: 10.1016/j.cell.2018.12.009. Epub 2019 Jan 17. Cell. 2019. PMID: 30661757 Free PMC article.
90 results