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Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose.
Toma L, Stancu CS, Botez GM, Sima AV, Simionescu M. Toma L, et al. Among authors: simionescu m. Biochem Biophys Res Commun. 2009 Dec 18;390(3):877-82. doi: 10.1016/j.bbrc.2009.10.066. Epub 2009 Oct 20. Biochem Biophys Res Commun. 2009. PMID: 19850013
Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes.
Manea SA, Antonescu ML, Fenyo IM, Raicu M, Simionescu M, Manea A. Manea SA, et al. Among authors: simionescu m. Redox Biol. 2018 Jun;16:332-343. doi: 10.1016/j.redox.2018.03.011. Epub 2018 Mar 17. Redox Biol. 2018. PMID: 29587244 Free PMC article.
High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ.
Manea A, Manea SA, Todirita A, Albulescu IC, Raicu M, Sasson S, Simionescu M. Manea A, et al. Among authors: simionescu m. Cell Tissue Res. 2015 Aug;361(2):593-604. doi: 10.1007/s00441-015-2120-0. Epub 2015 Feb 27. Cell Tissue Res. 2015. PMID: 25722086
Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells.
Odent Grigorescu G, Rosca AM, Preda MB, Tutuianu R, Simionescu M, Burlacu A. Odent Grigorescu G, et al. Among authors: simionescu m. J Tissue Eng Regen Med. 2017 Nov;11(11):3241-3252. doi: 10.1002/term.2233. Epub 2016 Dec 12. J Tissue Eng Regen Med. 2017. PMID: 27943613
CO2 laser increases the regenerative capacity of human adipose-derived stem cells by a mechanism involving the redox state and enhanced secretion of pro-angiogenic molecules.
Constantin A, Dumitrescu M, Mihai Corotchi MC, Jianu D, Simionescu M. Constantin A, et al. Among authors: simionescu m. Lasers Med Sci. 2017 Jan;32(1):117-127. doi: 10.1007/s10103-016-2093-6. Epub 2016 Oct 20. Lasers Med Sci. 2017. PMID: 27761667
Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules.
Butoi ED, Gan AM, Manduteanu I, Stan D, Calin M, Pirvulescu M, Koenen RR, Weber C, Simionescu M. Butoi ED, et al. Among authors: simionescu m. Biochim Biophys Acta. 2011 Dec;1813(12):2026-35. doi: 10.1016/j.bbamcr.2011.08.009. Epub 2011 Aug 22. Biochim Biophys Acta. 2011. PMID: 21888931
Monocyte chemoattractant protein-1--a major contributor to the inflammatory process associated with diabetes.
Dragomir E, Simionescu M. Dragomir E, et al. Among authors: simionescu m. Arch Physiol Biochem. 2006 Oct-Dec;112(4-5):239-44. doi: 10.1080/13813450601094672. Arch Physiol Biochem. 2006. PMID: 17178597 Review.
Cellular mechanisms and signalling pathways activated by high glucose and AGE-albumin in the aortic endothelium.
Popov D, Simionescu M. Popov D, et al. Among authors: simionescu m. Arch Physiol Biochem. 2006 Oct-Dec;112(4-5):265-73. doi: 10.1080/13813450601094573. Arch Physiol Biochem. 2006. PMID: 17178601 Review.
Inflammation in atherosclerosis: a cause or a result of vascular disorders?
Manduteanu I, Simionescu M. Manduteanu I, et al. Among authors: simionescu m. J Cell Mol Med. 2012 Sep;16(9):1978-90. doi: 10.1111/j.1582-4934.2012.01552.x. J Cell Mol Med. 2012. PMID: 22348535 Free PMC article. Review.
Effect of depletion of monocytes/macrophages on early aortic valve lesion in experimental hyperlipidemia.
Calin MV, Manduteanu I, Dragomir E, Dragan E, Nicolae M, Gan AM, Simionescu M. Calin MV, et al. Among authors: simionescu m. Cell Tissue Res. 2009 May;336(2):237-48. doi: 10.1007/s00441-009-0765-2. Epub 2009 Mar 20. Cell Tissue Res. 2009. PMID: 19301037
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