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Long-term azithromycin for bronchiolitis obliterans syndrome after lung transplantation.
Gottlieb J, Szangolies J, Koehnlein T, Golpon H, Simon A, Welte T. Gottlieb J, et al. Among authors: simon a. Transplantation. 2008 Jan 15;85(1):36-41. doi: 10.1097/01.tp.0000295981.84633.bc. Transplantation. 2008. PMID: 18192909 Clinical Trial.
A cutoff value of <20% in pretreatment BAL had a negative predictive value of 0.91 for treatment response. Thirty-three patients (40%) showed disease progression during follow-up (491+/-165 days). ...Beneficial effects on gastroesophageal reflux disease may be
A cutoff value of <20% in pretreatment BAL had a negative predictive value of 0.91 for treatment response. Thirty-three pat
Absence of PERV specific humoral immune response in baboons after transplantation of porcine cells or organs.
Martin U, Tacke SJ, Simon AR, Schröder C, Wiebe K, Lapin B, Haverich A, Denner J, Steinhoff G. Martin U, et al. Among authors: simon ar. Transpl Int. 2002 Jul;15(7):361-8. doi: 10.1007/s00147-002-0428-7. Epub 2002 Jun 22. Transpl Int. 2002. PMID: 12122513
Xenotransplantation of pig organs seems a promising way of overcoming the prevailing limitation on allotransplantation due to donor numbers. ...In a retrospective study 15 immunosuppressed baboons were tested for a specific immune response against PERV after …
Xenotransplantation of pig organs seems a promising way of overcoming the prevailing limitation on allotransplantation due to donor n …
Community-acquired respiratory viral infections in lung transplant recipients: a single season cohort study.
Gottlieb J, Schulz TF, Welte T, Fuehner T, Dierich M, Simon AR, Engelmann I. Gottlieb J, et al. Among authors: simon ar. Transplantation. 2009 May 27;87(10):1530-7. doi: 10.1097/TP.0b013e3181a4857d. Transplantation. 2009. PMID: 19461490
METHODS: A single-center prospective cohort study was performed in LTx-outpatients between October 31, 2005 and April 30, 2006. ...Symptomatic CARV-infection proved to be a significant covariate for 1-year BOS-free survival in multivariate analysis (P=0.002, adjuste …
METHODS: A single-center prospective cohort study was performed in LTx-outpatients between October 31, 2005 and April 30, 2006. ...Sy …
Size reduction of donor organs in pediatric lung transplantation.
Mueller C, Hansen G, Ballmann M, Schwerk N, Simon AR, Goerler H, Strueber M. Mueller C, et al. Among authors: simon ar. Pediatr Transplant. 2010 May;14(3):364-8. doi: 10.1111/j.1399-3046.2009.01242.x. Epub 2009 Sep 28. Pediatr Transplant. 2010. PMID: 19793226
Preoperatively, there was a trend toward a higher rate of mechanical ventilation and a higher capillary pCO(2) in the reduced size group. ...Our study demonstrates that reduced size LTx in children is a reliable therapeutic option that provides results …
Preoperatively, there was a trend toward a higher rate of mechanical ventilation and a higher capillary pCO(2) in the r …
Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.
Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Díez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Lesèche G, Thomas P, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A. Warnecke G, et al. Among authors: simon ar. Lancet Respir Med. 2018 May;6(5):357-367. doi: 10.1016/S2213-2600(18)30136-X. Epub 2018 Apr 9. Lancet Respir Med. 2018. PMID: 29650408 Clinical Trial.
BACKGROUND: Severe primary graft dysfunction (PGD) of grade 3 (PGD3) is a common serious complication following lung transplantation. ...Eligible donors were younger than 65 years old with a ratio of partial pressure of oxygen in arterial blood to the fraction of in …
BACKGROUND: Severe primary graft dysfunction (PGD) of grade 3 (PGD3) is a common serious complication following lung transplantation. …
Lung Preservation With Perfadex or Celsior in Clinical Transplantation: A Retrospective Single-Center Analysis of Outcomes.
Gohrbandt B, Simon AR, Warnecke G, Fischer S, Hagl C, Niehaus A, Gottlieb J, Welte T, Haverich A, Strueber M. Gohrbandt B, et al. Among authors: simon ar. Transplantation. 2015 Sep;99(9):1933-9. doi: 10.1097/TP.0000000000000578. Transplantation. 2015. PMID: 25651311
BACKGROUND: Despite improvement of lung preservation by the introduction of low-potassium dextran (LPD) solution, ischemia-reperfusion injury remains a major contributor to early post-lung transplant graft dysfunction and mortality. ...CONCLUSIONS: A trend toward be …
BACKGROUND: Despite improvement of lung preservation by the introduction of low-potassium dextran (LPD) solution, ischemia-reperfusion injur …
Viremia after lung transplant: a cohort study on risk factors and symptoms associated with detection of Epstein-Barr virus.
Mattner F, Hesse N, Fegbeutel C, Strüber M, Gottlieb J, Sohr D, Welte T, Schulz TF, Simon AR, Engelmann I. Mattner F, et al. Among authors: simon ar. Prog Transplant. 2012 Jun;22(2):155-60. doi: 10.7182/pit2012771. Prog Transplant. 2012. PMID: 22878072
Background-The frequency and impact of detection of Epstein-Barr virus in the blood of lung and heart-lung transplant recipients in the postoperative period is poorly characterized.Objective-To investigate the frequency of virus detection, associated clinical symptoms and risk fa …
Background-The frequency and impact of detection of Epstein-Barr virus in the blood of lung and heart-lung transplant recipients in the post …
Lung function early after lung transplantation is correlated with the frequency of regulatory T cells.
Nakagiri T, Warnecke G, Avsar M, Thissen S, Kruse B, Kühn C, Ziehme P, Knöfel AK, Madrahimov N, Okumura M, Sawa Y, Gottlieb J, Simon AR, Haverich A, Strüber M. Nakagiri T, et al. Among authors: simon ar. Surg Today. 2012 Feb;42(3):250-8. doi: 10.1007/s00595-011-0087-3. Epub 2011 Dec 17. Surg Today. 2012. PMID: 22173646
Single-centre experience with oral ribavirin in lung transplant recipients with paramyxovirus infections.
Fuehner T, Dierich M, Duesberg C, DeWall C, Welte T, Haverich A, Warnecke G, Simon AR, Gottlieb J. Fuehner T, et al. Among authors: simon ar. Antivir Ther. 2011;16(5):733-40. doi: 10.3851/IMP1811. Antivir Ther. 2011. PMID: 21817195 Clinical Trial.
Ribavirin represents a possible treatment option although the outcome on graft function and BOS incidence is unknown. METHODS: We analysed outcomes of all PV infections in lung/heart-lung recipients between September 2006 and April 2009 in a single centre. ...RESULT …
Ribavirin represents a possible treatment option although the outcome on graft function and BOS incidence is unknown. METHODS: We ana …
Graft-protective effects of the HMG-CoA reductase inhibitor pravastatin after lung transplantation--a propensity score analysis with 23 years of follow-up.
Li Y, Gottlieb J, Ma D, Kuehn C, Strueber M, Welte T, Simon AR, Warnecke G, Haverich A. Li Y, et al. Among authors: simon ar. Transplantation. 2011 Aug 27;92(4):486-92. doi: 10.1097/TP.0b013e318225670d. Transplantation. 2011. PMID: 21712756
BACKGROUND: To determine whether the hydroxy-3-methylglutaryl coenzyme A reductase inhibitor pravastatin has a graft-protective effect, we retrospectively analyzed 502 patients who had undergone lung transplantation in Hannover. ...CONCLUSION: These findings suggest …
BACKGROUND: To determine whether the hydroxy-3-methylglutaryl coenzyme A reductase inhibitor pravastatin has a graft-protectiv …
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