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The biological impact of mass-spectrometry-based proteomics.
Cravatt BF, Simon GM, Yates JR 3rd. Cravatt BF, et al. Nature. 2007 Dec 13;450(7172):991-1000. doi: 10.1038/nature06525. Nature. 2007. PMID: 18075578 Review.
Quantitative reactivity profiling predicts functional cysteines in proteomes.
Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF. Weerapana E, et al. Nature. 2010 Dec 9;468(7325):790-5. doi: 10.1038/nature09472. Epub 2010 Nov 17. Nature. 2010. PMID: 21085121 Free PMC article.
Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study.
Simon GM, Cravatt BF. Simon GM, et al. J Biol Chem. 2010 Apr 9;285(15):11051-5. doi: 10.1074/jbc.R109.097600. Epub 2010 Feb 10. J Biol Chem. 2010. PMID: 20147750 Free PMC article. Review.
Comparative assessment of large-scale proteomic studies of apoptotic proteolysis.
Simon GM, Dix MM, Cravatt BF. Simon GM, et al. ACS Chem Biol. 2009 Jun 19;4(6):401-8. doi: 10.1021/cb900082q. ACS Chem Biol. 2009. PMID: 19415908 Free PMC article.
Challenges for the 'chemical-systems' biologist.
Simon GM, Cravatt BF. Simon GM, et al. Nat Chem Biol. 2008 Nov;4(11):639-42. doi: 10.1038/nchembio1108-639. Nat Chem Biol. 2008. PMID: 18936742 No abstract available.
Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes.
Hanson SR, Hsu TL, Weerapana E, Kishikawa K, Simon GM, Cravatt BF, Wong CH. Hanson SR, et al. J Am Chem Soc. 2007 Jun 13;129(23):7266-7. doi: 10.1021/ja0724083. Epub 2007 May 17. J Am Chem Soc. 2007. PMID: 17506567 Free PMC article. No abstract available.
The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice.
Kopp F, Komatsu T, Nomura DK, Trauger SA, Thomas JR, Siuzdak G, Simon GM, Cravatt BF. Kopp F, et al. Chem Biol. 2010 Aug 27;17(8):831-40. doi: 10.1016/j.chembiol.2010.06.009. Chem Biol. 2010. PMID: 20797612 Free PMC article.
Quantitative Chemical Proteomic Profiling of the in Vivo Targets of Reactive Drug Metabolites.
Whitby LR, Obach RS, Simon GM, Hayward MM, Cravatt BF. Whitby LR, et al. Among authors: simon gm. ACS Chem Biol. 2017 Aug 18;12(8):2040-2050. doi: 10.1021/acschembio.7b00346. Epub 2017 Jun 21. ACS Chem Biol. 2017. PMID: 28636309 Free PMC article.
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