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Optimal two-stage designs for phase II clinical trials.
Simon R. Simon R. Control Clin Trials. 1989 Mar;10(1):1-10. doi: 10.1016/0197-2456(89)90015-9. Control Clin Trials. 1989. PMID: 2702835
Optimal two-stage designs for clinical trials with binary response.
Thall PF, Simon R, Ellenberg SS, Shrager R. Thall PF, et al. Stat Med. 1988 May;7(5):571-9. doi: 10.1002/sim.4780070504. Stat Med. 1988. PMID: 3387716
Selecting the best dose when a monotonic dose-response relation exists.
Russek-Cohen E, Simon RM. Russek-Cohen E, et al. Stat Med. 1994 Jan 15;13(1):87-95. doi: 10.1002/sim.4780130110. Stat Med. 1994. PMID: 9061843
Qualitative interactions in multifactor studies.
Russek-Cohen E, Simon RM. Russek-Cohen E, et al. Biometrics. 1993 Jun;49(2):467-77. Biometrics. 1993. PMID: 8369382
In some situations, the methodology of Gail and Simon (1985, Biometrics 41, 361-372) is shown to be appropriate. Their procedure assumes independent estimates of treatment effect for each subset of patients and this may not be appropriate for the generalizations we propose …
In some situations, the methodology of Gail and Simon (1985, Biometrics 41, 361-372) is shown to be appropriate. Their procedure assu …
Evaluating treatments when a gender by treatment interaction may exist.
Russek-Cohen E, Simon RM. Russek-Cohen E, et al. Stat Med. 1997 Feb 28;16(4):455-64. doi: 10.1002/(sici)1097-0258(19970228)16:4<455::aid-sim382>3.0.co;2-y. Stat Med. 1997. PMID: 9044532
Note on the design of multi-institution three-treatment studies.
Makuch RW, Simon RM. Makuch RW, et al. Cancer Clin Trials. 1978 Winter;1(4):301-3. Cancer Clin Trials. 1978. PMID: 757147
Extension of one-sided test to multiple treatment trials.
Chen TT, Simon RM. Chen TT, et al. Control Clin Trials. 1994 Apr;15(2):124-34. doi: 10.1016/0197-2456(94)90016-7. Control Clin Trials. 1994. PMID: 8205803
Recent developments in the design of phase II clinical trials.
Thall PF, Simon RM. Thall PF, et al. Cancer Treat Res. 1995;75:49-71. doi: 10.1007/978-1-4615-2009-2_3. Cancer Treat Res. 1995. PMID: 7640167 Review. No abstract available.
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