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Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300.
Simone C, Stiegler P, Forcales SV, Bagella L, De Luca A, Sartorelli V, Giordano A, Puri PL. Simone C, et al. Oncogene. 2004 Mar 18;23(12):2177-87. doi: 10.1038/sj.onc.1207327. Oncogene. 2004. PMID: 14968110
The C/H3 region of p300 was found to co-purify deacetylase activity from nuclear cell extracts. A prototype of class I histone deacetylases, HDAC1, interacts with p300 C/H3 domain in vitro and in vivo. The p300-binding protein E1A competes with HDAC1 for C/H3 …
The C/H3 region of p300 was found to co-purify deacetylase activity from nuclear cell extracts. A prototype of class I histone deacet …
Activation of MyoD-dependent transcription by cdk9/cyclin T2.
Simone C, Stiegler P, Bagella L, Pucci B, Bellan C, De Falco G, De Luca A, Guanti G, Puri PL, Giordano A. Simone C, et al. Oncogene. 2002 Jun 13;21(26):4137-48. doi: 10.1038/sj.onc.1205493. Oncogene. 2002. PMID: 12037670
Physical interaction between pRb and cdk9/cyclinT2 complex.
Simone C, Bagella L, Bellan C, Giordano A. Simone C, et al. Oncogene. 2002 Jun 13;21(26):4158-65. doi: 10.1038/sj.onc.1205511. Oncogene. 2002. PMID: 12037672
The interaction involves the region composed of residues 129-195 of cdk9, cyclinT2 (1-642 aa) and the C-terminal domain of pRb (835-928 aa). We located the minimal region of cdk9 phosphorylation on the C-terminus of pRb, by identifying the residues between 793 and 8 …
The interaction involves the region composed of residues 129-195 of cdk9, cyclinT2 (1-642 aa) and the C-terminal domain of pRb (835-9 …
Differentiation-induced radioresistance in muscle cells.
Latella L, Lukas J, Simone C, Puri PL, Bartek J. Latella L, et al. Mol Cell Biol. 2004 Jul;24(14):6350-61. doi: 10.1128/MCB.24.14.6350-6361.2004. Mol Cell Biol. 2004. PMID: 15226436 Free PMC article.
New insight in cdk9 function: from Tat to MyoD.
Simone C, Giordano A. Simone C, et al. Front Biosci. 2001 Sep 1;6:D1073-82. doi: 10.2741/simone. Front Biosci. 2001. PMID: 11532614 Review.
p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.
Grossi V, Peserico A, Tezil T, Simone C. Grossi V, et al. World J Gastroenterol. 2014 Aug 7;20(29):9744-58. doi: 10.3748/wjg.v20.i29.9744. World J Gastroenterol. 2014. PMID: 25110412 Free PMC article. Review.
Characterization of the rs2802292 SNP identifies FOXO3A as a modifier locus predicting cancer risk in patients with PJS and PHTS hamartomatous polyposis syndromes.
Forte G, Grossi V, Celestini V, Lucisano G, Scardapane M, Varvara D, Patruno M, Bagnulo R, Loconte D, Giunti L, Petracca A, Giglio S, Genuardi M, Pellegrini F, Resta N, Simone C. Forte G, et al. BMC Cancer. 2014 Sep 11;14:661. doi: 10.1186/1471-2407-14-661. BMC Cancer. 2014. PMID: 25208626 Free PMC article.
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