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Page 1
Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.
van Olst L, Simonton B, Edwards AJ, Forsyth AV, Boles J, Jamshidi P, Watson T, Shepard N, Krainc T, Argue BM, Zhang Z, Kuruvilla J, Camp L, Li M, Xu H, Norman JL, Cahan J, Vassar R, Chen J, Castellani RJ, Nicoll JA, Boche D, Gate D. van Olst L, et al. Among authors: simonton b. Nat Med. 2025 May;31(5):1604-1616. doi: 10.1038/s41591-025-03574-1. Epub 2025 Mar 6. Nat Med. 2025. PMID: 40050704 Free PMC article.
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.
Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D. Piehl N, et al. Among authors: simonton b. Cell. 2022 Dec 22;185(26):5028-5039.e13. doi: 10.1016/j.cell.2022.11.019. Epub 2022 Dec 13. Cell. 2022. PMID: 36516855 Free PMC article.
Epigenetic dysregulation in Alzheimer's disease peripheral immunity.
Ramakrishnan A, Piehl N, Simonton B, Parikh M, Zhang Z, Teregulova V, van Olst L, Gate D. Ramakrishnan A, et al. Among authors: simonton b. Neuron. 2024 Apr 17;112(8):1235-1248.e5. doi: 10.1016/j.neuron.2024.01.013. Epub 2024 Feb 9. Neuron. 2024. PMID: 38340719 Free PMC article.
Author Correction: Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.
van Olst L, Simonton B, Edwards AJ, Forsyth AV, Boles J, Jamshidi P, Watson T, Shepard N, Krainc T, Argue BM, Zhang Z, Kuruvilla J, Camp L, Li M, Xu H, Norman JL, Cahan J, Vassar R, Chen J, Castellani RJ, Nicoll JA, Boche D, Gate D. van Olst L, et al. Among authors: simonton b. Nat Med. 2025 May;31(5):1712. doi: 10.1038/s41591-025-03664-0. Nat Med. 2025. PMID: 40155563 Free PMC article. No abstract available.
Integrated antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy.
Almubarak HF, Tan W, Hoffmann AD, Sun Y, Wei J, El-Shennawy L, Squires JR, Dashzeveg NK, Simonton B, Jia Y, Iyer R, Xu Y, Nicolaescu V, Elli D, Randall GC, Schipma MJ, Swaminathan S, Ison MG, Liu H, Fang D, Shen Y. Almubarak HF, et al. Among authors: simonton b. iScience. 2025 Sep 17;28(10):113584. doi: 10.1016/j.isci.2025.113584. eCollection 2025 Oct 17. iScience. 2025. PMID: 41126882 Free PMC article.
Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy.
Almubarak HF, Tan W, Hoffmann AD, Sun Y, Wei J, El-Shennawy L, Squires JR, Dashzeveg NK, Simonton B, Jia Y, Iyer R, Xu Y, Nicolaescu V, Elli D, Randall GC, Schipma MJ, Swaminathan S, Ison MG, Liu H, Fang D, Shen Y. Almubarak HF, et al. Among authors: simonton b. bioRxiv [Preprint]. 2024 Aug 20:2024.03.01.582176. doi: 10.1101/2024.03.01.582176. bioRxiv. 2024. Update in: iScience. 2025 Sep 17;28(10):113584. doi: 10.1016/j.isci.2025.113584. PMID: 38496411 Free PMC article. Updated. Preprint.
Simultaneous CRISPR screening and spatial transcriptomics reveals intracellular, intercellular, and functional transcriptional circuits.
Binan L, Danquah S, Valakh V, Simonton B, Bezney J, Nehme R, Cleary B, Farhi SL. Binan L, et al. Among authors: simonton b. bioRxiv [Preprint]. 2023 Dec 1:2023.11.30.569494. doi: 10.1101/2023.11.30.569494. bioRxiv. 2023. Update in: Cell. 2025 Apr 17;188(8):2141-2158.e18. doi: 10.1016/j.cell.2025.02.012. PMID: 38076932 Free PMC article. Updated. Preprint.
19 results