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Direct study of DNA-protein interactions in repressed and active chromatin in living cells.
Kladde MP, Xu M, Simpson RT. Kladde MP, et al. Among authors: simpson rt. EMBO J. 1996 Nov 15;15(22):6290-300. EMBO J. 1996. PMID: 8947052 Free PMC article.
The DNA repair protein yKu80 regulates the function of recombination enhancer during yeast mating type switching.
Ruan C, Workman JL, Simpson RT. Ruan C, et al. Among authors: simpson rt. Mol Cell Biol. 2005 Oct;25(19):8476-85. doi: 10.1128/MCB.25.19.8476-8485.2005. Mol Cell Biol. 2005. PMID: 16166630 Free PMC article.
A single heterochromatin boundary element imposes position-independent antisilencing activity in Saccharomyces cerevisiae minichromosomes.
Chakraborty SA, Simpson RT, Grigoryev SA. Chakraborty SA, et al. Among authors: simpson rt. PLoS One. 2011;6(9):e24835. doi: 10.1371/journal.pone.0024835. Epub 2011 Sep 16. PLoS One. 2011. PMID: 21949764 Free PMC article.
Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure.
Surcel A, Koshland D, Ma H, Simpson RT. Surcel A, et al. Among authors: simpson rt. PLoS One. 2008 Jun 11;3(6):e2453. doi: 10.1371/journal.pone.0002453. PLoS One. 2008. PMID: 18545699 Free PMC article.
Purification of native, defined chromatin segments.
Simpson RT, Ducker CE, Diller JD, Ruan C. Simpson RT, et al. Methods Enzymol. 2004;375:158-70. doi: 10.1016/s0076-6879(03)75010-1. Methods Enzymol. 2004. PMID: 14870665 No abstract available.
Global chromatin structure of 45,000 base pairs of chromosome III in a- and alpha-cell yeast and during mating-type switching.
Ercan S, Simpson RT. Ercan S, et al. Among authors: simpson rt. Mol Cell Biol. 2004 Nov;24(22):10026-35. doi: 10.1128/MCB.24.22.10026-10035.2004. Mol Cell Biol. 2004. PMID: 15509803 Free PMC article.
Yeast alpha 2 repressor positions nucleosomes in TRP1/ARS1 chromatin.
Roth SY, Dean A, Simpson RT. Roth SY, et al. Among authors: simpson rt. Mol Cell Biol. 1990 May;10(5):2247-60. doi: 10.1128/mcb.10.5.2247. Mol Cell Biol. 1990. PMID: 2183026 Free PMC article.
The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.
Cooper JP, Roth SY, Simpson RT. Cooper JP, et al. Among authors: simpson rt. Genes Dev. 1994 Jun 15;8(12):1400-10. doi: 10.1101/gad.8.12.1400. Genes Dev. 1994. PMID: 7926740
In vivo methods to analyze chromatin structure.
Simpson RT. Simpson RT. Curr Opin Genet Dev. 1999 Apr;9(2):225-9. doi: 10.1016/S0959-437X(99)80033-1. Curr Opin Genet Dev. 1999. PMID: 10322144 Review.
DNA methyltransferases as probes of chromatin structure in vivo.
Kladde MP, Xu M, Simpson RT. Kladde MP, et al. Among authors: simpson rt. Methods Enzymol. 1999;304:431-47. doi: 10.1016/s0076-6879(99)04026-4. Methods Enzymol. 1999. PMID: 10372375 No abstract available.
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