Simpson TI - Search Results

1

Pax6; a pleiotropic player in development.

Simpson TI, Price DJ. Simpson TI, et al. Bioessays. 2002 Nov;24(11):1041-51. doi: 10.1002/bies.10174. Bioessays. 2002. PMID: 12386935 Review.

2

Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

Simpson TI, Pratt T, Mason JO, Price DJ. Simpson TI, et al. Neural Dev. 2009 Jun 5;4:19. doi: 10.1186/1749-8104-4-19. Neural Dev. 2009. PMID: 19500363 Free PMC article.

3

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.

Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ. Manuel M, et al. Among authors: simpson ti. Development. 2007 Feb;134(3):545-55. doi: 10.1242/dev.02764. Epub 2007 Jan 3. Development. 2007. PMID: 17202185 Free PMC article.

4

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells.

Pinson J, Simpson TI, Mason JO, Price DJ. Pinson J, et al. Among authors: simpson ti. BMC Dev Biol. 2006 May 25;6:25. doi: 10.1186/1471-213X-6-25. BMC Dev Biol. 2006. PMID: 16725027 Free PMC article.

5

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse.

Pratt T, Tian NM, Simpson TI, Mason JO, Price DJ. Pratt T, et al. Among authors: simpson ti. Development. 2004 Aug;131(15):3773-84. doi: 10.1242/dev.01246. Epub 2004 Jul 7. Development. 2004. PMID: 15240555 Free PMC article.

6

Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

Pratt T, Quinn JC, Simpson TI, West JD, Mason JO, Price DJ. Pratt T, et al. Among authors: simpson ti. J Neurosci. 2002 Oct 1;22(19):8523-31. doi: 10.1523/JNEUROSCI.22-19-08523.2002. J Neurosci. 2002. PMID: 12351726 Free PMC article.

7

Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

Dorà NJ, Crookshanks AJ, Leung KK, Simpson TI, Mason JO, Price DJ, West JD. Dorà NJ, et al. Among authors: simpson ti. Transgenic Res. 2016 Oct;25(5):679-92. doi: 10.1007/s11248-016-9962-4. Epub 2016 May 30. Transgenic Res. 2016. PMID: 27240603 Free PMC article.

8

Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb.

Mi D, Carr CB, Georgala PA, Huang YT, Manuel MN, Jeanes E, Niisato E, Sansom SN, Livesey FJ, Theil T, Hasenpusch-Theil K, Simpson TI, Mason JO, Price DJ. Mi D, et al. Among authors: simpson ti. Neuron. 2013 Apr 24;78(2):269-84. doi: 10.1016/j.neuron.2013.02.012. Neuron. 2013. PMID: 23622063 Free PMC article.

9

Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.

Zaki PA, Collinson JM, Toraiwa J, Simpson TI, Price DJ, Quinn JC. Zaki PA, et al. Among authors: simpson ti. BMC Dev Biol. 2006 Oct 9;6:46. doi: 10.1186/1471-213X-6-46. BMC Dev Biol. 2006. PMID: 17029624 Free PMC article.

10

Long-range downstream enhancers are essential for Pax6 expression.

Kleinjan DA, Seawright A, Mella S, Carr CB, Tyas DA, Simpson TI, Mason JO, Price DJ, van Heyningen V. Kleinjan DA, et al. Among authors: simpson ti. Dev Biol. 2006 Nov 15;299(2):563-81. doi: 10.1016/j.ydbio.2006.08.060. Epub 2006 Aug 30. Dev Biol. 2006. PMID: 17014839 Free PMC article.

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