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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 2
1948 1
1972 1
1974 1
1975 1
1980 1
1981 1
1982 1
1983 1
1985 1
1986 1
1987 1
1989 1
1991 1
1992 2
1993 2
1994 4
1995 2
1996 1
1997 7
1998 7
1999 7
2000 2
2001 2
2002 5
2003 6
2004 4
2005 5
2006 9
2007 11
2008 7
2009 6
2010 9
2011 9
2012 12
2013 19
2014 16
2015 11
2016 20
2017 10
2018 14
2019 17
2020 11
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Article type
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236 results
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Page 1
Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.
Rajman L, Chwalek K, Sinclair DA. Rajman L, et al. Among authors: sinclair da. Cell Metab. 2018 Mar 6;27(3):529-547. doi: 10.1016/j.cmet.2018.02.011. Cell Metab. 2018. PMID: 29514064 Free PMC article. Review.
Epigenetic changes during aging and their reprogramming potential.
Kane AE, Sinclair DA. Kane AE, et al. Among authors: sinclair da. Crit Rev Biochem Mol Biol. 2019 Feb;54(1):61-83. doi: 10.1080/10409238.2019.1570075. Epub 2019 Mar 1. Crit Rev Biochem Mol Biol. 2019. PMID: 30822165 Free PMC article. Review.
Sirtuin activators and inhibitors: Promises, achievements, and challenges.
Dai H, Sinclair DA, Ellis JL, Steegborn C. Dai H, et al. Among authors: sinclair da. Pharmacol Ther. 2018 Aug;188:140-154. doi: 10.1016/j.pharmthera.2018.03.004. Epub 2018 Mar 22. Pharmacol Ther. 2018. PMID: 29577959 Free PMC article. Review.
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds.
Bonkowski MS, Sinclair DA. Bonkowski MS, et al. Among authors: sinclair da. Nat Rev Mol Cell Biol. 2016 Nov;17(11):679-690. doi: 10.1038/nrm.2016.93. Epub 2016 Aug 24. Nat Rev Mol Cell Biol. 2016. PMID: 27552971 Free PMC article. Review.
Interventions to Slow Aging in Humans: Are We Ready?
Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L. Longo VD, et al. Among authors: sinclair da. Aging Cell. 2015 Aug;14(4):497-510. doi: 10.1111/acel.12338. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25902704 Free PMC article. Review.
NAD+ in Brain Aging and Neurodegenerative Disorders.
Lautrup S, Sinclair DA, Mattson MP, Fang EF. Lautrup S, et al. Among authors: sinclair da. Cell Metab. 2019 Oct 1;30(4):630-655. doi: 10.1016/j.cmet.2019.09.001. Cell Metab. 2019. PMID: 31577933 Free PMC article. Review.
Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases.
Kane AE, Sinclair DA. Kane AE, et al. Among authors: sinclair da. Circ Res. 2018 Sep 14;123(7):868-885. doi: 10.1161/CIRCRESAHA.118.312498. Circ Res. 2018. PMID: 30355082 Free PMC article. Review.
The intersection between aging and cardiovascular disease.
North BJ, Sinclair DA. North BJ, et al. Among authors: sinclair da. Circ Res. 2012 Apr 13;110(8):1097-108. doi: 10.1161/CIRCRESAHA.111.246876. Circ Res. 2012. PMID: 22499900 Free PMC article. Review.
Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.
Das A, Huang GX, Bonkowski MS, Longchamp A, Li C, Schultz MB, Kim LJ, Osborne B, Joshi S, Lu Y, Treviño-Villarreal JH, Kang MJ, Hung TT, Lee B, Williams EO, Igarashi M, Mitchell JR, Wu LE, Turner N, Arany Z, Guarente L, Sinclair DA. Das A, et al. Among authors: sinclair da. Cell. 2018 Mar 22;173(1):74-89.e20. doi: 10.1016/j.cell.2018.02.008. Cell. 2018. PMID: 29570999 Free PMC article.
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R. Mitchell SJ, et al. Among authors: sinclair da. Cell Metab. 2018 Mar 6;27(3):667-676.e4. doi: 10.1016/j.cmet.2018.02.001. Cell Metab. 2018. PMID: 29514072 Free PMC article.
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