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Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease.
Amano H, Chaudhury A, Rodriguez-Aguayo C, Lu L, Akhanov V, Catic A, Popov YV, Verdin E, Johnson H, Stossi F, Sinclair DA, Nakamaru-Ogiso E, Lopez-Berestein G, Chang JT, Neilson JR, Meeker A, Finegold M, Baur JA, Sahin E. Amano H, et al. Among authors: sinclair da. Cell Metab. 2019 Jun 4;29(6):1274-1290.e9. doi: 10.1016/j.cmet.2019.03.001. Epub 2019 Mar 28. Cell Metab. 2019. PMID: 30930169 Free PMC article.
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet.
Mitchell SJ, Martin-Montalvo A, Mercken EM, Palacios HH, Ward TM, Abulwerdi G, Minor RK, Vlasuk GP, Ellis JL, Sinclair DA, Dawson J, Allison DB, Zhang Y, Becker KG, Bernier M, de Cabo R. Mitchell SJ, et al. Among authors: sinclair da. Cell Rep. 2014 Mar 13;6(5):836-43. doi: 10.1016/j.celrep.2014.01.031. Epub 2014 Feb 27. Cell Rep. 2014. PMID: 24582957 Free PMC article.
Germline energetics, aging, and female infertility.
Tilly JL, Sinclair DA. Tilly JL, et al. Among authors: sinclair da. Cell Metab. 2013 Jun 4;17(6):838-850. doi: 10.1016/j.cmet.2013.05.007. Cell Metab. 2013. PMID: 23747243 Free PMC article. Review.
Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.
Das A, Huang GX, Bonkowski MS, Longchamp A, Li C, Schultz MB, Kim LJ, Osborne B, Joshi S, Lu Y, TreviƱo-Villarreal JH, Kang MJ, Hung TT, Lee B, Williams EO, Igarashi M, Mitchell JR, Wu LE, Turner N, Arany Z, Guarente L, Sinclair DA. Das A, et al. Among authors: sinclair da. Cell. 2018 Mar 22;173(1):74-89.e20. doi: 10.1016/j.cell.2018.02.008. Cell. 2018. PMID: 29570999 Free PMC article.
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