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Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.
van Meurs J, van Lent P, Stoop R, Holthuysen A, Singer I, Bayne E, Mudgett J, Poole R, Billinghurst C, van der Kraan P, Buma P, van den Berg W. van Meurs J, et al. Arthritis Rheum. 1999 Oct;42(10):2074-84. doi: 10.1002/1529-0131(199910)42:10<2074::AID-ANR7>3.0.CO;2-5. Arthritis Rheum. 1999. PMID: 10524678 Free article.
Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.
Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, Singer II, Donatelli SA, Weidner JR, Williams HR, Mumford RA, Lohmander LS. Lark MW, et al. Among authors: singer ii. J Clin Invest. 1997 Jul 1;100(1):93-106. doi: 10.1172/JCI119526. J Clin Invest. 1997. PMID: 9202061 Free PMC article.
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