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Structure and mechanism of helicases and nucleic acid translocases.
Singleton MR, Dillingham MS, Wigley DB. Singleton MR, et al. Annu Rev Biochem. 2007;76:23-50. doi: 10.1146/annurev.biochem.76.052305.115300. Annu Rev Biochem. 2007. PMID: 17506634 Review.
A molecular gate for DNA (comment on DOI 10.1002/bies.201600207).
Singleton MR. Singleton MR. Bioessays. 2017 Apr;39(4). doi: 10.1002/bies.201700021. Epub 2017 Mar 7. Bioessays. 2017. PMID: 28266712 No abstract available.
Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks.
Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC, Wigley DB. Singleton MR, et al. Nature. 2004 Nov 11;432(7014):187-93. doi: 10.1038/nature02988. Nature. 2004. PMID: 15538360
Multiple roles for ATP hydrolysis in nucleic acid modifying enzymes.
Singleton MR, Wigley DB. Singleton MR, et al. EMBO J. 2003 Sep 15;22(18):4579-83. doi: 10.1093/emboj/cdg441. EMBO J. 2003. PMID: 12970170 Free PMC article. Review.
Modularity and specialization in superfamily 1 and 2 helicases.
Singleton MR, Wigley DB. Singleton MR, et al. J Bacteriol. 2002 Apr;184(7):1819-26. doi: 10.1128/jb.184.7.1819-1826.2002. J Bacteriol. 2002. PMID: 11889086 Free PMC article. Review. No abstract available.
Structure of yeast kinetochore Ndc10 DNA-binding domain reveals unexpected evolutionary relationship to tyrosine recombinases.
Perriches T, Singleton MR. Perriches T, et al. Among authors: singleton mr. J Biol Chem. 2012 Feb 10;287(7):5173-9. doi: 10.1074/jbc.C111.318501. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215672 Free PMC article.
Insights into kinetochore-DNA interactions from the structure of Cep3Delta.
Purvis A, Singleton MR. Purvis A, et al. Among authors: singleton mr. EMBO Rep. 2008 Jan;9(1):56-62. doi: 10.1038/sj.embor.7401139. Epub 2007 Dec 7. EMBO Rep. 2008. PMID: 18064045 Free PMC article.
Structural studies of RFCCtf18 reveal a novel chromatin recruitment role for Dcc1.
Wade BO, Liu HW, Samora CP, Uhlmann F, Singleton MR. Wade BO, et al. Among authors: singleton mr. EMBO Rep. 2017 Apr;18(4):558-568. doi: 10.15252/embr.201642825. Epub 2017 Feb 10. EMBO Rep. 2017. PMID: 28188145 Free PMC article.
Structural analysis of DNA replication fork reversal by RecG.
Singleton MR, Scaife S, Wigley DB. Singleton MR, et al. Cell. 2001 Oct 5;107(1):79-89. doi: 10.1016/s0092-8674(01)00501-3. Cell. 2001. PMID: 11595187
Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides.
Singleton MR, Sawaya MR, Ellenberger T, Wigley DB. Singleton MR, et al. Cell. 2000 Jun 9;101(6):589-600. doi: 10.1016/s0092-8674(00)80871-5. Cell. 2000. PMID: 10892646
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