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58 results
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Orexin/hypocretin plays a role in the response to physiological disequilibrium.
Sinton CM. Sinton CM. Sleep Med Rev. 2011 Jun;15(3):197-207. doi: 10.1016/j.smrv.2010.12.003. Epub 2011 Jan 26. Sleep Med Rev. 2011. PMID: 21269851 Review.
Promotion of Wakefulness and Energy Expenditure by Orexin-A in the Ventrolateral Preoptic Area.
Mavanji V, Perez-Leighton CE, Kotz CM, Billington CJ, Parthasarathy S, Sinton CM, Teske JA. Mavanji V, et al. Among authors: sinton cm. Sleep. 2015 Sep 1;38(9):1361-70. doi: 10.5665/sleep.4970. Sleep. 2015. PMID: 25845696 Free PMC article.
To eat or to sleep? Orexin in the regulation of feeding and wakefulness.
Willie JT, Chemelli RM, Sinton CM, Yanagisawa M. Willie JT, et al. Among authors: sinton cm. Annu Rev Neurosci. 2001;24:429-58. doi: 10.1146/annurev.neuro.24.1.429. Annu Rev Neurosci. 2001. PMID: 11283317 Review.
The effects of leptin on REM sleep and slow wave delta in rats are reversed by food deprivation.
Sinton CM, Fitch TE, Gershenfeld HK. Sinton CM, et al. J Sleep Res. 1999 Sep;8(3):197-203. doi: 10.1046/j.1365-2869.1999.00158.x. J Sleep Res. 1999. PMID: 10476006
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M. Chemelli RM, et al. Among authors: sinton cm. Cell. 1999 Aug 20;98(4):437-51. doi: 10.1016/s0092-8674(00)81973-x. Cell. 1999. PMID: 10481909
Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.
Willie JT, Renthal W, Chemelli RM, Miller MS, Scammell TE, Yanagisawa M, Sinton CM. Willie JT, et al. Among authors: sinton cm. Neuroscience. 2005;130(4):983-95. doi: 10.1016/j.neuroscience.2004.10.005. Neuroscience. 2005. PMID: 15652995
Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
Willie JT, Chemelli RM, Sinton CM, Tokita S, Williams SC, Kisanuki YY, Marcus JN, Lee C, Elmquist JK, Kohlmeier KA, Leonard CS, Richardson JA, Hammer RE, Yanagisawa M. Willie JT, et al. Among authors: sinton cm. Neuron. 2003 Jun 5;38(5):715-30. doi: 10.1016/s0896-6273(03)00330-1. Neuron. 2003. PMID: 12797957
Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.
Mieda M, Willie JT, Hara J, Sinton CM, Sakurai T, Yanagisawa M. Mieda M, et al. Among authors: sinton cm. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4649-54. doi: 10.1073/pnas.0400590101. Epub 2004 Mar 16. Proc Natl Acad Sci U S A. 2004. PMID: 15070772 Free PMC article.
Behavioral and biochemical dissociation of arousal and homeostatic sleep need influenced by prior wakeful experience in mice.
Suzuki A, Sinton CM, Greene RW, Yanagisawa M. Suzuki A, et al. Among authors: sinton cm. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10288-93. doi: 10.1073/pnas.1308295110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716651 Free PMC article.
Validation of a novel method to interrupt sleep in the mouse.
Sinton CM, Kovakkattu D, Friese RS. Sinton CM, et al. J Neurosci Methods. 2009 Oct 30;184(1):71-8. doi: 10.1016/j.jneumeth.2009.07.026. Epub 2009 Jul 29. J Neurosci Methods. 2009. PMID: 19646474
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