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N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation.
Bowie LE, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, Hung CLK, Patel S, Xia J, Hertz NT, Ross CA, Litchfield DW, Sipione S, Truant R. Bowie LE, et al. Among authors: sipione s. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7081-E7090. doi: 10.1073/pnas.1801772115. Epub 2018 Jul 9. Proc Natl Acad Sci U S A. 2018. PMID: 29987005 Free PMC article.
Disease-modifying effects of ganglioside GM1 in Huntington's disease models.
Alpaugh M, Galleguillos D, Forero J, Morales LC, Lackey SW, Kar P, Di Pardo A, Holt A, Kerr BJ, Todd KG, Baker GB, Fouad K, Sipione S. Alpaugh M, et al. Among authors: sipione s. EMBO Mol Med. 2017 Nov;9(11):1537-1557. doi: 10.15252/emmm.201707763. EMBO Mol Med. 2017. PMID: 28993428 Free PMC article.
Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells.
Watson AES, de Almeida MMA, Dittmann NL, Li Y, Torabi P, Footz T, Vetere G, Galleguillos D, Sipione S, Cardona AE, Voronova A. Watson AES, et al. Among authors: sipione s. Stem Cell Reports. 2021 Aug 10;16(8):1968-1984. doi: 10.1016/j.stemcr.2021.06.010. Epub 2021 Jul 15. Stem Cell Reports. 2021. PMID: 34270934 Free PMC article.
A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling.
van der Veen JN, Lingrell S, McCloskey N, LeBlond ND, Galleguillos D, Zhao YY, Curtis JM, Sipione S, Fullerton MD, Vance DE, Jacobs RL. van der Veen JN, et al. Among authors: sipione s. FASEB J. 2019 Apr;33(4):5045-5057. doi: 10.1096/fj.201802117R. Epub 2019 Jan 7. FASEB J. 2019. PMID: 30615497
Thus, treatments to reduce the PC:PE ratio in liver may protect against the development of hepatic insulin resistance.-Van der Veen, J. N., Lingrell, S., McCloskey, N., LeBlond, N. D., Galleguillos, D., Zhao, Y. Y., Curtis, J. M., Sipione, S., Fullerton, M. D …
Thus, treatments to reduce the PC:PE ratio in liver may protect against the development of hepatic insulin resistance.-Van der Veen, J. N., …
Anti-inflammatory role of GM1 and other gangliosides on microglia.
Galleguillos D, Wang Q, Steinberg N, Zaidi A, Shrivastava G, Dhami K, Daskhan GC, Schmidt EN, Dworsky-Fried Z, Giuliani F, Churchward M, Power C, Todd K, Taylor A, Macauley MS, Sipione S. Galleguillos D, et al. Among authors: sipione s. J Neuroinflammation. 2022 Jan 6;19(1):9. doi: 10.1186/s12974-021-02374-x. J Neuroinflammation. 2022. PMID: 34991625 Free PMC article.
55 results