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Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity.
Citarella A, Sibille G, Moi D, Dimasi A, Braga T, Col LD, Ruberto L, Pieraccini S, Sironi M, Micale N, Schirmeister T, Fasano V, Silvani A, Giannini C, Gribaudo G, Passarella D. Citarella A, et al. Among authors: sironi m. Bioorg Med Chem. 2025 Oct 1;128:118258. doi: 10.1016/j.bmc.2025.118258. Epub 2025 May 23. Bioorg Med Chem. 2025. PMID: 40435714 Free article.
In silico design of tubulin-targeted antimitotic peptides.
Pieraccini S, Saladino G, Cappelletti G, Cartelli D, Francescato P, Speranza G, Manitto P, Sironi M. Pieraccini S, et al. Among authors: sironi m. Nat Chem. 2009 Nov;1(8):642-8. doi: 10.1038/nchem.401. Epub 2009 Oct 23. Nat Chem. 2009. PMID: 21378956
Camptothecin-7-yl-methanthiole: semisynthesis and biological evaluation.
Christodoulou MS, Zunino F, Zuco V, Borrelli S, Comi D, Fontana G, Martinelli M, Lorens JB, Evensen L, Sironi M, Pieraccini S, Dalla Via L, Gia OM, Passarella D. Christodoulou MS, et al. Among authors: sironi m. ChemMedChem. 2012 Dec;7(12):2134-43. doi: 10.1002/cmdc.201200322. Epub 2012 Oct 19. ChemMedChem. 2012. PMID: 23086693
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins.
Christodoulou MS, Sacchetti A, Ronchetti V, Caufin S, Silvani A, Lesma G, Fontana G, Minicone F, Riva B, Ventura M, Lahtela-Kakkonen M, Jarho E, Zuco V, Zunino F, Martinet N, Dapiaggi F, Pieraccini S, Sironi M, Dalla Via L, Gia OM, Passarella D. Christodoulou MS, et al. Among authors: sironi m. Bioorg Med Chem. 2013 Nov 15;21(22):6920-8. doi: 10.1016/j.bmc.2013.09.030. Epub 2013 Sep 19. Bioorg Med Chem. 2013. PMID: 24103429
531 results