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Initiation of neural induction by FGF signalling before gastrulation.
Streit A, Berliner AJ, Papanayotou C, Sirulnik A, Stern CD. Streit A, et al. Among authors: sirulnik a. Nature. 2000 Jul 6;406(6791):74-8. doi: 10.1038/35017617. Nature. 2000. PMID: 10894544
Using ERNI as a marker, we present evidence that neural induction begins before gastrulation--much earlier in development than previously thought. We show that the organizer and some of its precursor cells produce a fibroblast growth factor signal, which can initiat …
Using ERNI as a marker, we present evidence that neural induction begins before gastrulation--much earlier in development than previo …
The identification and characterization of a STAT5 gene signature in hematologic malignancies.
Sonkin D, Palmer M, Rong X, Horrigan K, Regnier CH, Fanton C, Holash J, Pinzon-Ortiz M, Squires M, Sirulnik A, Radimerski T, Schlegel R, Morrissey M, Cao ZA. Sonkin D, et al. Among authors: sirulnik a. Cancer Biomark. 2015;15(1):79-87. doi: 10.3233/CBM-140434. Cancer Biomark. 2015. PMID: 25524945
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor.
Marango J, Shimoyama M, Nishio H, Meyer JA, Min DJ, Sirulnik A, Martinez-Martinez Y, Chesi M, Bergsagel PL, Zhou MM, Waxman S, Leibovitch BA, Walsh MJ, Licht JD. Marango J, et al. Among authors: sirulnik a. Blood. 2008 Mar 15;111(6):3145-54. doi: 10.1182/blood-2007-06-092122. Epub 2007 Dec 21. Blood. 2008. PMID: 18156491 Free PMC article.
MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis.
van Loo PF, Hangalapura BN, Thordardottir S, Gibbins JD, Veninga H, Hendriks LJA, Kramer A, Roovers RC, Leenders M, de Kruif J, Doornbos RP, Sirulnik A, Throsby M, Logtenberg T, Dolstra H, Bakker ABH. van Loo PF, et al. Among authors: sirulnik a. Expert Opin Biol Ther. 2019 Jul;19(7):721-733. doi: 10.1080/14712598.2019.1623200. Expert Opin Biol Ther. 2019. PMID: 31286786
Invasive insect effects on nitrogen cycling and host physiology are not tightly linked.
Rubino L, Charles S, Sirulnik AG, Tuininga AR, Lewis JD. Rubino L, et al. Among authors: sirulnik ag. Tree Physiol. 2015 Feb;35(2):124-33. doi: 10.1093/treephys/tpv004. Epub 2015 Feb 25. Tree Physiol. 2015. PMID: 25721368
Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis.
Cervantes F, Vannucchi AM, Kiladjian JJ, Al-Ali HK, Sirulnik A, Stalbovskaya V, McQuitty M, Hunter DS, Levy RS, Passamonti F, Barbui T, Barosi G, Harrison CN, Knoops L, Gisslinger H; COMFORT-II investigators. Cervantes F, et al. Among authors: sirulnik a. Blood. 2013 Dec 12;122(25):4047-53. doi: 10.1182/blood-2013-02-485888. Epub 2013 Oct 30. Blood. 2013. PMID: 24174625 Clinical Trial.
Health-related quality of life and symptoms in patients with myelofibrosis treated with ruxolitinib versus best available therapy.
Harrison CN, Mesa RA, Kiladjian JJ, Al-Ali HK, Gisslinger H, Knoops L, Squier M, Sirulnik A, Mendelson E, Zhou X, Copley-Merriman C, Hunter DS, Levy RS, Cervantes F, Passamonti F, Barbui T, Barosi G, Vannucchi AM. Harrison CN, et al. Among authors: sirulnik a. Br J Haematol. 2013 Jul;162(2):229-39. doi: 10.1111/bjh.12375. Epub 2013 May 14. Br J Haematol. 2013. PMID: 23672349 Clinical Trial.
Patient preferences for reducing toxicities of treatments for gastrointestinal stromal tumor (GIST).
Hauber AB, Gonzalez JM, Coombs J, Sirulnik A, Palacios D, Scherzer N. Hauber AB, et al. Among authors: sirulnik a. Patient Prefer Adherence. 2011;5:307-14. doi: 10.2147/PPA.S20445. Epub 2011 Jun 24. Patient Prefer Adherence. 2011. PMID: 21792302 Free PMC article.
A USA registry of gastrointestinal stromal tumor patients: changes in practice over time and differences between community and academic practices.
Pisters PWT, Blanke CD, von Mehren M, Picus J, Sirulnik A, Stealey E, Trent JC; reGISTry Steering Committee. Pisters PWT, et al. Among authors: sirulnik a. Ann Oncol. 2011 Nov;22(11):2523-2529. doi: 10.1093/annonc/mdq773. Epub 2011 Apr 4. Ann Oncol. 2011. PMID: 21464155 Free article. Clinical Trial.
Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia.
Attar EC, De Angelo DJ, Supko JG, D'Amato F, Zahrieh D, Sirulnik A, Wadleigh M, Ballen KK, McAfee S, Miller KB, Levine J, Galinsky I, Trehu EG, Schenkein D, Neuberg D, Stone RM, Amrein PC. Attar EC, et al. Among authors: sirulnik a. Clin Cancer Res. 2008 Mar 1;14(5):1446-54. doi: 10.1158/1078-0432.CCR-07-4626. Clin Cancer Res. 2008. PMID: 18316568 Free article. Clinical Trial.
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