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Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
Siska PJ, Decking SM, Babl N, Matos C, Bruss C, Singer K, Klitzke J, Schön M, Simeth J, Köstler J, Siegmund H, Ugele I, Paulus M, Dietl A, Kolodova K, Steines L, Freitag K, Peuker A, Schönhammer G, Raithel J, Graf B, Geismann F, Lubnow M, Mack M, Hau P, Bohr C, Burkhardt R, Gessner A, Salzberger B, Wagner R, Hanses F, Hitzenbichler F, Heudobler D, Lüke F, Pukrop T, Herr W, Wolff D, Spang R, Poeck H, Hoffmann P, Jantsch J, Brochhausen C, Lunz D, Rehli M, Kreutz M, Renner K. Siska PJ, et al. J Clin Invest. 2021 Nov 15;131(22):e148225. doi: 10.1172/JCI148225. J Clin Invest. 2021. PMID: 34779418 Free PMC article.
Immunometabolism in cancer at a glance.
Singer K, Cheng WC, Kreutz M, Ho PC, Siska PJ. Singer K, et al. Among authors: siska pj. Dis Model Mech. 2018 Aug 2;11(8):dmm034272. doi: 10.1242/dmm.034272. Dis Model Mech. 2018. PMID: 30076128 Free PMC article. Review.
Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells.
Renner K, Seilbeck A, Kauer N, Ugele I, Siska PJ, Brummer C, Bruss C, Decking SM, Fante M, Schmidt A, Hammon K, Singer K, Klobuch S, Thomas S, Gottfried E, Peter K, Kreutz M. Renner K, et al. Among authors: siska pj. Front Pharmacol. 2018 Nov 2;9:1258. doi: 10.3389/fphar.2018.01258. eCollection 2018. Front Pharmacol. 2018. PMID: 30450049 Free PMC article.
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M. Renner K, et al. Among authors: siska pj. Cell Rep. 2019 Oct 1;29(1):135-150.e9. doi: 10.1016/j.celrep.2019.08.068. Cell Rep. 2019. PMID: 31577944 Free article.
1,25-dihydroxyvitamin-D3 but not the clinically applied marker 25-hydroxyvitamin-D3 predicts survival after stem cell transplantation.
Peter K, Siska PJ, Roider T, Matos C, Bruns H, Renner K, Singer K, Weber D, Güllstorf M, Kröger N, Wolff D, Herr W, Ayuk F, Holler E, Stark K, Heid IM, Kreutz M. Peter K, et al. Among authors: siska pj. Bone Marrow Transplant. 2021 Feb;56(2):419-433. doi: 10.1038/s41409-020-01031-w. Epub 2020 Aug 27. Bone Marrow Transplant. 2021. PMID: 32855442 Free PMC article.
The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients.
Spanier G, Ugele I, Nieberle F, Symeou L, Schmidhofer S, Brand A, Meier J, Spoerl S, Krupar R, Rümmele P, Siska P, Renner K, Peter K, Gerken M, Beckhove P, Reichert TE, Kreutz M, Singer K. Spanier G, et al. Cancer Lett. 2021 Feb 28;499:209-219. doi: 10.1016/j.canlet.2020.11.029. Epub 2020 Dec 1. Cancer Lett. 2021. PMID: 33276040 Free article.
40 results