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Ruthenium-catalyzed cycloadditions of 1-haloalkynes with nitrile oxides and organic azides: synthesis of 4-haloisoxazoles and 5-halotriazoles.
Oakdale JS, Sit RK, Fokin VV. Oakdale JS, et al. Among authors: sit rk. Chemistry. 2014 Aug 25;20(35):11101-10. doi: 10.1002/chem.201402559. Epub 2014 Jul 24. Chemistry. 2014. PMID: 25059647 Free PMC article.
Stereoselective 1,3-insertions of rhodium(II) azavinyl carbenes.
Chuprakov S, Worrell BT, Selander N, Sit RK, Fokin VV. Chuprakov S, et al. Among authors: sit rk. J Am Chem Soc. 2014 Jan 8;136(1):195-202. doi: 10.1021/ja408185c. Epub 2013 Dec 17. J Am Chem Soc. 2014. PMID: 24295389 Free PMC article.
Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification.
Sit RK, Fokin VV, Amitai G, Sharpless KB, Taylor P, Radić Z. Sit RK, et al. J Med Chem. 2014 Feb 27;57(4):1378-89. doi: 10.1021/jm401650z. Epub 2014 Feb 7. J Med Chem. 2014. PMID: 24571195 Free PMC article.
New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases.
Sit RK, Radić Z, Gerardi V, Zhang L, Garcia E, Katalinić M, Amitai G, Kovarik Z, Fokin VV, Sharpless KB, Taylor P. Sit RK, et al. J Biol Chem. 2011 Jun 3;286(22):19422-30. doi: 10.1074/jbc.M111.230656. Epub 2011 Apr 4. J Biol Chem. 2011. PMID: 21464125 Free PMC article.
Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure.
Taylor P, Yan-Jye S, Momper J, Hou W, Camacho-Hernandez GA, Radic' Z, Rosenberg Y, Kovarik Z, Sit R, Sharpless KB. Taylor P, et al. Among authors: sit r. Chem Biol Interact. 2019 Aug 1;308:194-197. doi: 10.1016/j.cbi.2019.05.015. Epub 2019 May 14. Chem Biol Interact. 2019. PMID: 31100277 Review.
Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes.
Kovarik Z, Maček Hrvat N, Katalinić M, Sit RK, Paradyse A, Žunec S, Musilek K, Fokin VV, Taylor P, Radić Z. Kovarik Z, et al. Among authors: sit rk. Chem Res Toxicol. 2015 May 18;28(5):1036-44. doi: 10.1021/acs.chemrestox.5b00060. Epub 2015 Apr 16. Chem Res Toxicol. 2015. PMID: 25835984 Free PMC article.
Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates.
Radić Z, Sit RK, Garcia E, Zhang L, Berend S, Kovarik Z, Amitai G, Fokin VV, Barry Sharpless K, Taylor P. Radić Z, et al. Among authors: sit rk. Chem Biol Interact. 2013 Mar 25;203(1):67-71. doi: 10.1016/j.cbi.2012.08.014. Epub 2012 Sep 4. Chem Biol Interact. 2013. PMID: 22975155 Free PMC article.
Centrally acting oximes in reactivation of tabun-phosphoramidated AChE.
Kovarik Z, Maček N, Sit RK, Radić Z, Fokin VV, Barry Sharpless K, Taylor P. Kovarik Z, et al. Among authors: sit rk. Chem Biol Interact. 2013 Mar 25;203(1):77-80. doi: 10.1016/j.cbi.2012.08.019. Epub 2012 Sep 7. Chem Biol Interact. 2013. PMID: 22960624 Free PMC article.
Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases.
Radić Z, Sit RK, Kovarik Z, Berend S, Garcia E, Zhang L, Amitai G, Green C, Radić B, Fokin VV, Sharpless KB, Taylor P. Radić Z, et al. Among authors: sit rk. J Biol Chem. 2012 Apr 6;287(15):11798-809. doi: 10.1074/jbc.M111.333732. Epub 2012 Feb 16. J Biol Chem. 2012. PMID: 22343626 Free PMC article.
Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure.
Sit RK, Kovarik Z, Maček Hrvat N, Žunec S, Green C, Fokin VV, Sharpless KB, Radić Z, Taylor P. Sit RK, et al. J Pharmacol Exp Ther. 2018 Nov;367(2):363-372. doi: 10.1124/jpet.118.249383. Epub 2018 Sep 6. J Pharmacol Exp Ther. 2018. PMID: 30190337 Free PMC article.
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