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Reconstruction and visualization of fiber and laminar structure in the normal human heart from ex vivo diffusion tensor magnetic resonance imaging (DTMRI) data.
Rohmer D, Sitek A, Gullberg GT. Rohmer D, et al. Invest Radiol. 2007 Nov;42(11):777-89. doi: 10.1097/RLI.0b013e3181238330. Invest Radiol. 2007. PMID: 18030201
OBJECTIVE: The human heart is composed of a helical network of muscle fibers organized to form sheets that are separated by cleavage planes responsible for the orthotropic mechanical properties of cardiac muscle. ...CONCLUSIONS: A visualization algorithm was develop …
OBJECTIVE: The human heart is composed of a helical network of muscle fibers organized to form sheets that are separated by cleavage …
Optimizing analysis, visualization, and navigation of large image data sets: one 5000-section CT scan can ruin your whole day.
Andriole KP, Wolfe JM, Khorasani R, Treves ST, Getty DJ, Jacobson FL, Steigner ML, Pan JJ, Sitek A, Seltzer SE. Andriole KP, et al. Radiology. 2011 May;259(2):346-62. doi: 10.1148/radiol.11091276. Radiology. 2011. PMID: 21502391 Free PMC article. Review.
This may require a paradigm shift in the radiologic interpretation process. As human observers, radiologists must search for, detect, and interpret targets. ...This historical psychophysical and technical review touches on a broad range of disciplines but focuses ma …
This may require a paradigm shift in the radiologic interpretation process. As human observers, radiologists must search for, detect, …
Tomographic reconstruction using an adaptive tetrahedral mesh defined by a point cloud.
Sitek A, Huesman RH, Gullberg GT. Sitek A, et al. IEEE Trans Med Imaging. 2006 Sep;25(9):1172-9. doi: 10.1109/tmi.2006.879319. IEEE Trans Med Imaging. 2006. PMID: 16967802
A method for three-dimensional (3-D) tomographic reconstruction is developed using a point cloud image representation. A point cloud is a set of points (nodes) in space, where each node of the point cloud is characterized by its position and intensity.
A method for three-dimensional (3-D) tomographic reconstruction is developed using a point cloud image representation. A
Method of generating multiple sets of experimental phantom data.
Sitek A, Reutter BW, Huesman RH, Gullberg GT. Sitek A, et al. J Nucl Med. 2006 Jul;47(7):1187-92. J Nucl Med. 2006. PMID: 16818954
We applied it to an anthropomorphic torso phantom with a cardiac insert, using a SPECT system with attenuation correction. First, real data were acquired. ...The acquired database was successful in the generation of static and dynamic sinograms for which the myocard …
We applied it to an anthropomorphic torso phantom with a cardiac insert, using a SPECT system with attenuation correction. Fir …
Correction for ambiguous solutions in factor analysis using a penalized least squares objective.
Sitek A, Gullberg GT, Huesman RH. Sitek A, et al. IEEE Trans Med Imaging. 2002 Mar;21(3):216-25. doi: 10.1109/42.996340. IEEE Trans Med Imaging. 2002. PMID: 11989846
In this paper, a method to correct for ambiguous FADS solutions has been developed. A nonambiguous solution (to within certain scaling factors) is obtained by constructing and minimizing a new objective function. ...In our method, this objective function is m …
In this paper, a method to correct for ambiguous FADS solutions has been developed. A nonambiguous solution (to within certain …
Dual-tracer PET using generalized factor analysis of dynamic sequences.
El Fakhri G, Trott CM, Sitek A, Bonab A, Alpert NM. El Fakhri G, et al. Mol Imaging Biol. 2013 Dec;15(6):666-74. doi: 10.1007/s11307-013-0631-1. Mol Imaging Biol. 2013. PMID: 23636489 Free PMC article.
PROCEDURES: To address this limitation, we developed a novel approach based on generalized factor analysis of dynamic sequences (GFADS) that exploits spatio-temporal differences between radiotracers and applied it to near-simultaneous imaging of 2-deoxy-2-[(18)F]fluoro-D-g …
PROCEDURES: To address this limitation, we developed a novel approach based on generalized factor analysis of dynamic sequences (GFAD …
Comparison and prognostic validation of multiple methods of quantification of myocardial blood flow with 82Rb PET.
Murthy VL, Lee BC, Sitek A, Naya M, Moody J, Polavarapu V, Ficaro EP, Di Carli MF. Murthy VL, et al. J Nucl Med. 2014 Dec;55(12):1952-8. doi: 10.2967/jnumed.114.145342. J Nucl Med. 2014. PMID: 25429160
We sought to compare the differences in these methods and models and their impact on prognostic assessment in a large clinical dataset. ...The input function was derived using a region of interest (ROI) semiautomatically placed in the region of the mitral valve, fac …
We sought to compare the differences in these methods and models and their impact on prognostic assessment in a large clinical datase …
Quantification of Myocardial Perfusion Reserve Using Dynamic SPECT Imaging in Humans: A Feasibility Study.
Ben-Haim S, Murthy VL, Breault C, Allie R, Sitek A, Roth N, Fantony J, Moore SC, Park MA, Kijewski M, Haroon A, Slomka P, Erlandsson K, Baavour R, Zilberstien Y, Bomanji J, Di Carli MF. Ben-Haim S, et al. J Nucl Med. 2013 Jun;54(6):873-9. doi: 10.2967/jnumed.112.109652. Epub 2013 Apr 11. J Nucl Med. 2013. PMID: 23578996 Free PMC article. Clinical Trial.
We evaluated the feasibility of dynamic tomographic SPECT imaging and quantification of a retention index to describe global and regional myocardial perfusion reserve using a dedicated solid-state cardiac camera. ...MPR index showed a stepwise reduction with …
We evaluated the feasibility of dynamic tomographic SPECT imaging and quantification of a retention index to describe global and regi …
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