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Formation of reversible disulfide bonds with the protein matrix of the endoplasmic reticulum correlates with the retention of unassembled Ig light chains.
Reddy P, Sparvoli A, Fagioli C, Fassina G, Sitia R. Reddy P, et al. Among authors: sitia r. EMBO J. 1996 May 1;15(9):2077-85. EMBO J. 1996. PMID: 8641273 Free PMC article.
Endoplasmic reticulum: a dynamic patchwork of specialized subregions.
Sitia R, Meldolesi J. Sitia R, et al. Mol Biol Cell. 1992 Oct;3(10):1067-72. doi: 10.1091/mbc.3.10.1067. Mol Biol Cell. 1992. PMID: 1421566 Free PMC article. Review. No abstract available.
Modulating secretion of antibodies.
Fra AM, Alberini C, Bet P, Finazzi D, Valetti C, Sitia R. Fra AM, et al. Among authors: sitia r. Ann Biol Clin (Paris). 1991;49(5):283-6. Ann Biol Clin (Paris). 1991. PMID: 1928844
Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum.
Valetti C, Grossi CE, Milstein C, Sitia R. Valetti C, et al. Among authors: sitia r. J Cell Biol. 1991 Nov;115(4):983-94. doi: 10.1083/jcb.115.4.983. J Cell Biol. 1991. PMID: 1955467 Free PMC article.
Protein degradation in the endoplasmic reticulum.
Klausner RD, Sitia R. Klausner RD, et al. Among authors: sitia r. Cell. 1990 Aug 24;62(4):611-4. doi: 10.1016/0092-8674(90)90104-m. Cell. 1990. PMID: 2201450 Review. No abstract available.
A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.
Rubartelli A, Cozzolino F, Talio M, Sitia R. Rubartelli A, et al. Among authors: sitia r. EMBO J. 1990 May;9(5):1503-10. EMBO J. 1990. PMID: 2328723 Free PMC article.
Regulation of membrane IgM expression in secretory B cells: translational and post-translational events.
Sitia R, Neuberger MS, Milstein C. Sitia R, et al. EMBO J. 1987 Dec 20;6(13):3969-77. EMBO J. 1987. PMID: 3127200 Free PMC article.
The differential effects of dithiothreitol and 2-mercaptoethanol on the secretion of partially and completely assembled immunoglobulins suggest that thiol-mediated retention does not take place in or beyond the Golgi.
Valetti C, Sitia R. Valetti C, et al. Among authors: sitia r. Mol Biol Cell. 1994 Dec;5(12):1311-24. doi: 10.1091/mbc.5.12.1311. Mol Biol Cell. 1994. PMID: 7696712 Free PMC article.
The efficiency of cysteine-mediated intracellular retention determines the differential fate of secretory IgA and IgM in B and plasma cells.
Guenzi S, Fra AM, Sparvoli A, Bet P, Rocco M, Sitia R. Guenzi S, et al. Among authors: sitia r. Eur J Immunol. 1994 Oct;24(10):2477-82. doi: 10.1002/eji.1830241033. Eur J Immunol. 1994. PMID: 7925577
Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation.
Fra AM, Fagioli C, Finazzi D, Sitia R, Alberini CM. Fra AM, et al. Among authors: sitia r. EMBO J. 1993 Dec;12(12):4755-61. EMBO J. 1993. PMID: 8223484 Free PMC article.
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