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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2001 3
2003 3
2004 2
2005 4
2006 2
2007 3
2008 3
2009 1
2010 2
2011 3
2013 2
2014 2
2015 1
2018 2
2019 2
2022 1
2024 0

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31 results

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Page 1
Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease.
Benito-Vicente A, Uribe KB, Jebari S, Galicia-Garcia U, Ostolaza H, Martin C. Benito-Vicente A, et al. Int J Mol Sci. 2018 Nov 1;19(11):3426. doi: 10.3390/ijms19113426. Int J Mol Sci. 2018. PMID: 30388787 Free PMC article. Review.
Malfunctioning of cholesterol metabolism is caused by multiple hereditary diseases, including Familial Hypercholesterolemia, Sitosterolemia Type C and Niemann-Pick Type C1. Of these, familial hypercholesterolemia (FH) is a common inherited autosomal co-dominant disorder ch …
Malfunctioning of cholesterol metabolism is caused by multiple hereditary diseases, including Familial Hypercholesterolemia, Sitosterolem
[Sitosterolemia (phytosterolemia)].
Lütjohann D. Lütjohann D. Internist (Berl). 2019 Aug;60(8):871-877. doi: 10.1007/s00108-019-0635-2. Internist (Berl). 2019. PMID: 31254003 Review. German.
Sitosterolemia or phytosterolemia is a rare autosomal recessive hereditary lipid storage disorder. ...Phytosterols are found mainly in vegetable oils, margarine, nuts, grains, soybeans and avocados. Patients with sitosterolemia show extreme phenotypic heterogeneity
Sitosterolemia or phytosterolemia is a rare autosomal recessive hereditary lipid storage disorder. ...Phytosterols are found mainly i
Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease.
Tada H, Nohara A, Inazu A, Sakuma N, Mabuchi H, Kawashiri MA. Tada H, et al. J Atheroscler Thromb. 2018 Sep 1;25(9):783-789. doi: 10.5551/jat.RV17024. Epub 2018 Jul 20. J Atheroscler Thromb. 2018. PMID: 30033951 Free PMC article. Review.
Sitosterolemia is a rare inherited disease characterized by increased levels of plant sterols, such as sitosterol. ...Regarding therapies, LDL apheresis, as well as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, could be useful for sitosterolemia,
Sitosterolemia is a rare inherited disease characterized by increased levels of plant sterols, such as sitosterol. ...Regarding thera
Features of chinese patients with sitosterolemia.
Zhou Z, Su X, Cai Y, Ting TH, Zhang W, Lin Y, Xu A, Mao X, Zeng C, Liu L, Li X. Zhou Z, et al. Lipids Health Dis. 2022 Jan 18;21(1):11. doi: 10.1186/s12944-021-01619-1. Lipids Health Dis. 2022. PMID: 35042526 Free PMC article. Review.
BACKGROUND: Sitosterolemia is a lipid disorder characterized by the accumulation of phytosterols in plasma and organs, caused by mutations in the ABCG5 and/or ABCG8 genes. ...The clinical features and molecular characteristics of Chinese patients with sitosterolemia
BACKGROUND: Sitosterolemia is a lipid disorder characterized by the accumulation of phytosterols in plasma and organs, caused by muta …
Ezetimibe.
Darkes MJ, Poole RM, Goa KL. Darkes MJ, et al. Am J Cardiovasc Drugs. 2003;3(1):67-76; discussion 77-8. doi: 10.2165/00129784-200303010-00007. Am J Cardiovasc Drugs. 2003. PMID: 14727947 Review.
Ezetimibe plus a statin reduced LDL-C levels more than the maximum statin dose alone in a trial in patients with homozygous familial hypercholesterolemia and was effective in a placebo-controlled trial in patients with homozygous sitosterolemia. The drug was well tolerated …
Ezetimibe plus a statin reduced LDL-C levels more than the maximum statin dose alone in a trial in patients with homozygous familial hyperch …
Genetics of familial hypercholesterolemia.
Brautbar A, Leary E, Rasmussen K, Wilson DP, Steiner RD, Virani S. Brautbar A, et al. Curr Atheroscler Rep. 2015 Apr;17(4):491. doi: 10.1007/s11883-015-0491-z. Curr Atheroscler Rep. 2015. PMID: 25712136 Review.
Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated low-density lipoprotein (LDL) cholesterol and premature cardiovascular disease, with a prevalence of approximately 1 in 200-500 for heterozygotes in North America and Europe. Monogenic FH is …
Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated low-density lipoprotein (LDL) cholesterol and premature c …
Diagnosis and management of familial dyslipoproteinemias.
Kwiterovich PO Jr. Kwiterovich PO Jr. Curr Cardiol Rep. 2013 Jun;15(6):371. doi: 10.1007/s11886-013-0371-5. Curr Cardiol Rep. 2013. PMID: 23666884 Review.
These include FH, FDB, ARH, PCSK9 gain-of-function mutations, sitosterolemia and loss of 7 alpha hydroxylase. Hepatic overproduction of VLDL occurs in FCHL, hyperapoB, LDL subclass pattern B, FDH and syndrome X, often due to insulin resistance and resulting in high TG, ele …
These include FH, FDB, ARH, PCSK9 gain-of-function mutations, sitosterolemia and loss of 7 alpha hydroxylase. Hepatic overproduction …
ABCG5/ABCG8 in cholesterol excretion and atherosclerosis.
Yu XH, Qian K, Jiang N, Zheng XL, Cayabyab FS, Tang CK. Yu XH, et al. Clin Chim Acta. 2014 Jan 20;428:82-8. doi: 10.1016/j.cca.2013.11.010. Epub 2013 Nov 16. Clin Chim Acta. 2014. PMID: 24252657 Review.
Liver X receptor is the major positive regulator of ABCG5 and ABCG8 expression. Mutations in either of the two genes cause sitosterolemia, a condition in which cholesterol and plant sterols accumulate in the circulation leading to premature cardiovascular disease. ...
Liver X receptor is the major positive regulator of ABCG5 and ABCG8 expression. Mutations in either of the two genes cause sitosterolemia
Genetic basis of sitosterolemia.
Lee MH, Lu K, Patel SB. Lee MH, et al. Curr Opin Lipidol. 2001 Apr;12(2):141-9. doi: 10.1097/00041433-200104000-00007. Curr Opin Lipidol. 2001. PMID: 11264985 Free PMC article. Review.
In sitosterolemia, a rare autosomal recessive disorder, affected individuals hyperabsorb and retain not only cholesterol but also all other sterols, including plant and shellfish sterols from the intestine. ...Mutations in two tandem ABC genes, ABCG5 and ABCG8, encoding st …
In sitosterolemia, a rare autosomal recessive disorder, affected individuals hyperabsorb and retain not only cholesterol but also all …
Noncholesterol sterols.
Vecka M, Zak A, Tvrzická E. Vecka M, et al. Acta Univ Carol Med Monogr. 2008;154:5-101. Acta Univ Carol Med Monogr. 2008. PMID: 19283968 Review.
The compound in question, cholesterol, seems to be involved, but it sounds not to be crucial per se. The fact that the accumulation of phytosterols in sitosterolemia enhances the probability of early atherosclerosis onset further supports the hypothesis about some sterol ( …
The compound in question, cholesterol, seems to be involved, but it sounds not to be crucial per se. The fact that the accumulation of phyto …
31 results