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N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.
Gobbi M, Funicello M, Gerstbrein K, Holy M, Moya PR, Sotomayor R, Forray MI, Gysling K, Paluzzi S, Bonanno G, Reyes-Parada M, Sitte HH, Mennini T. Gobbi M, et al. Among authors: sitte hh. J Neurochem. 2008 Jun;105(5):1770-80. doi: 10.1111/j.1471-4159.2008.05272.x. Epub 2008 Feb 4. J Neurochem. 2008. PMID: 18248615 Free PMC article.
Currents in neurotransmitter transporters.
Gerstbrein K, Sitte HH. Gerstbrein K, et al. Among authors: sitte hh. Handb Exp Pharmacol. 2006;(175):95-111. doi: 10.1007/3-540-29784-7_5. Handb Exp Pharmacol. 2006. PMID: 16722232 Review.
The N terminus of monoamine transporters is a lever required for the action of amphetamines.
Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH. Sucic S, et al. Among authors: sitte hh. J Biol Chem. 2010 Apr 2;285(14):10924-38. doi: 10.1074/jbc.M109.083154. Epub 2010 Jan 29. J Biol Chem. 2010. PMID: 20118234 Free PMC article.
197 results