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The potential of drug-carrying immunoliposomes as anticancer agents. Commentary re: J. W. Park et al., Anti-HER2 immunoliposomes: enhanced efficacy due to targeted delivery. Clin. Cancer Res., 8: 1172-1181, 2002.
Siwak DR, Tari AM, Lopez-Berestein G. Siwak DR, et al. Clin Cancer Res. 2002 Apr;8(4):955-6. Clin Cancer Res. 2002. PMID: 11948099 No abstract available.
Src activation regulates anoikis in human colon tumor cell lines.
Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE. Windham TC, et al. Among authors: siwak dr. Oncogene. 2002 Nov 7;21(51):7797-807. doi: 10.1038/sj.onc.1205989. Oncogene. 2002. PMID: 12420216
HER2/neu uses Akt to suppress retinoic acid response element binding activity in MDA-MB-453 breast cancer cells.
Siwak DR, Mendoza-Gamboa E, Tari AM. Siwak DR, et al. Int J Oncol. 2003 Dec;23(6):1739-45. Int J Oncol. 2003. PMID: 14612949
Liposomal antisense oligonucleotides for cancer therapy.
Siwak DR, Tari AM, Lopez-Berestein G. Siwak DR, et al. Methods Enzymol. 2004;387:241-53. doi: 10.1016/S0076-6879(04)87015-0. Methods Enzymol. 2004. PMID: 15172168 No abstract available.
The HER2/Grb2/Akt pathway regulates the DNA binding activity of AP-1 in breast cancer cells.
Mendoza-Gamboa E, Siwak DR, Tari AM. Mendoza-Gamboa E, et al. Among authors: siwak dr. Oncol Rep. 2004 Oct;12(4):903-8. Oncol Rep. 2004. PMID: 15375520
Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer.
Zhang Q, Bhola NE, Lui VW, Siwak DR, Thomas SM, Gubish CT, Siegfried JM, Mills GB, Shin D, Grandis JR. Zhang Q, et al. Among authors: siwak dr. Mol Cancer Ther. 2007 Apr;6(4):1414-24. doi: 10.1158/1535-7163.MCT-06-0678. Mol Cancer Ther. 2007. PMID: 17431120
Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells.
Aoki H, Iwado E, Eller MS, Kondo Y, Fujiwara K, Li GZ, Hess KR, Siwak DR, Sawaya R, Mills GB, Gilchrest BA, Kondo S. Aoki H, et al. Among authors: siwak dr. FASEB J. 2007 Sep;21(11):2918-30. doi: 10.1096/fj.06-6941com. Epub 2007 Apr 20. FASEB J. 2007. PMID: 17449721
Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance.
Ihle NT, Lemos R Jr, Wipf P, Yacoub A, Mitchell C, Siwak D, Mills GB, Dent P, Kirkpatrick DL, Powis G. Ihle NT, et al. Cancer Res. 2009 Jan 1;69(1):143-50. doi: 10.1158/0008-5472.CAN-07-6656. Cancer Res. 2009. PMID: 19117997 Free PMC article.
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition.
Mirzoeva OK, Das D, Heiser LM, Bhattacharya S, Siwak D, Gendelman R, Bayani N, Wang NJ, Neve RM, Guan Y, Hu Z, Knight Z, Feiler HS, Gascard P, Parvin B, Spellman PT, Shokat KM, Wyrobek AJ, Bissell MJ, McCormick F, Kuo WL, Mills GB, Gray JW, Korn WM. Mirzoeva OK, et al. Cancer Res. 2009 Jan 15;69(2):565-72. doi: 10.1158/0008-5472.CAN-08-3389. Cancer Res. 2009. PMID: 19147570 Free PMC article.
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