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Novel Aryloxyethyl Derivatives of 1-(1-Benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) Phosphorylation-Preferring Serotonin 5-HT1A Receptor-Biased Agonists with Robust Antidepressant-like Activity.
Sniecikowska J, Gluch-Lutwin M, Bucki A, Więckowska A, Siwek A, Jastrzebska-Wiesek M, Partyka A, Wilczyńska D, Pytka K, Pociecha K, Cios A, Wyska E, Wesołowska A, Pawłowski M, Varney MA, Newman-Tancredi A, Kolaczkowski M. Sniecikowska J, et al. Among authors: siwek a. J Med Chem. 2019 Mar 14;62(5):2750-2771. doi: 10.1021/acs.jmedchem.9b00062. Epub 2019 Mar 2. J Med Chem. 2019. PMID: 30721053
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity: part 2.
Herold F, Izbicki Ł, Chodkowski A, Dawidowski M, Król M, Kleps J, Turło J, Wolska I, Nowak G, Stachowicz K, Dybała M, Siwek A, Nowak M, Pieniazek E, Jarończyk M, Sylte I, Mazurek AP. Herold F, et al. Among authors: siwek a. Eur J Med Chem. 2009 Nov;44(11):4702-15. doi: 10.1016/j.ejmech.2009.07.007. Epub 2009 Jul 16. Eur J Med Chem. 2009. PMID: 19665823
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3.
Herold F, Chodkowski A, Izbicki Ł, Turło J, Dawidowski M, Kleps J, Nowak G, Stachowicz K, Dybała M, Siwek A, Mazurek AP, Mazurek A, Pluciński F. Herold F, et al. Among authors: siwek a. Eur J Med Chem. 2011 Jan;46(1):142-9. doi: 10.1016/j.ejmech.2010.10.026. Epub 2010 Oct 29. Eur J Med Chem. 2011. PMID: 21093118
Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT₁A/5-HT₂A/5-HT₇ and dopamine D₂/D₃ receptors.
Zajdel P, Marciniec K, Maślankiewicz A, Grychowska K, Satała G, Duszyńska B, Lenda T, Siwek A, Nowak G, Partyka A, Wróbel D, Jastrzębska-Więsek M, Bojarski AJ, Wesołowska A, Pawłowski M. Zajdel P, et al. Among authors: siwek a. Eur J Med Chem. 2013 Feb;60:42-50. doi: 10.1016/j.ejmech.2012.11.042. Epub 2012 Dec 5. Eur J Med Chem. 2013. PMID: 23279866
190 results