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Intracellular signal transduction pathways that control pancreatic beta-cell proliferation.
Sjöholm A. Sjöholm A. FEBS Lett. 1992 Oct 19;311(2):85-90. doi: 10.1016/0014-5793(92)81373-t. FEBS Lett. 1992. PMID: 1327880 Review.
Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells.
Grankvist N, Amable L, Honkanen RE, Sjöholm A, Ortsäter H. Grankvist N, et al. Among authors: sjoholm a. Diabetologia. 2012 Jul;55(7):2005-15. doi: 10.1007/s00125-012-2541-1. Epub 2012 Apr 12. Diabetologia. 2012. PMID: 22526606
Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, p38 MAPK, and JNK pathways.
Erdogdu O, Eriksson L, Xu H, Sjöholm A, Zhang Q, Nyström T. Erdogdu O, et al. Among authors: sjoholm a. J Mol Endocrinol. 2013 Mar 18;50(2):229-41. doi: 10.1530/JME-12-0166. Print 2013 Apr. J Mol Endocrinol. 2013. PMID: 23343509
Gene expression regulated by pioglitazone and exenatide in normal and diabetic rat islets exposed to lipotoxicity.
Ghanaat-Pour H, Sjöholm A. Ghanaat-Pour H, et al. Among authors: sjoholm a. Diabetes Metab Res Rev. 2009 Feb;25(2):163-84. doi: 10.1002/dmrr.896. Diabetes Metab Res Rev. 2009. PMID: 19065603
BLX-1002, a novel thiazolidinedione with no PPAR affinity, stimulates AMP-activated protein kinase activity, raises cytosolic Ca2+, and enhances glucose-stimulated insulin secretion in a PI3K-dependent manner.
Zhang F, Dey D, Bränström R, Forsberg L, Lu M, Zhang Q, Sjöholm A. Zhang F, et al. Among authors: sjoholm a. Am J Physiol Cell Physiol. 2009 Feb;296(2):C346-54. doi: 10.1152/ajpcell.00444.2008. Epub 2008 Dec 3. Am J Physiol Cell Physiol. 2009. PMID: 19052259
Global expression profiling of glucose-regulated genes in pancreatic islets of spontaneously diabetic Goto-Kakizaki rats.
Ghanaat-Pour H, Huang Z, Lehtihet M, Sjöholm A. Ghanaat-Pour H, et al. Among authors: sjoholm a. J Mol Endocrinol. 2007 Aug;39(2):135-50. doi: 10.1677/JME-07-0002. J Mol Endocrinol. 2007. PMID: 17693612
Attenuation of insulin secretion by insulin-like growth factor binding protein-1 in pancreatic beta-cells.
Zhang F, Sjöholm Å, Zhang Q. Zhang F, et al. Among authors: sjoholm a. Biochem Biophys Res Commun. 2007 Oct 12;362(1):152-157. doi: 10.1016/j.bbrc.2007.07.160. Epub 2007 Aug 7. Biochem Biophys Res Commun. 2007. PMID: 17693389
Pioglitazone acutely influences glucose-sensitive insulin secretion in normal and diabetic human islets.
Zhang F, Sjöholm A, Zhang Q. Zhang F, et al. Among authors: sjoholm a. Biochem Biophys Res Commun. 2006 Dec 22;351(3):750-5. doi: 10.1016/j.bbrc.2006.10.103. Epub 2006 Oct 30. Biochem Biophys Res Commun. 2006. PMID: 17084385
Glutamate inhibits protein phosphatases and promotes insulin exocytosis in pancreatic beta-cells.
Lehtihet M, Webb DL, Honkanen RE, Sjöholm A. Lehtihet M, et al. Among authors: sjoholm a. Biochem Biophys Res Commun. 2005 Mar 11;328(2):601-7. doi: 10.1016/j.bbrc.2005.01.024. Biochem Biophys Res Commun. 2005. PMID: 15694391
Inositol hexakisphosphate and sulfonylureas regulate beta-cell protein phosphatases.
Lehtihet M, Honkanen RE, Sjöholm A. Lehtihet M, et al. Among authors: sjoholm a. Biochem Biophys Res Commun. 2004 Apr 9;316(3):893-7. doi: 10.1016/j.bbrc.2004.02.144. Biochem Biophys Res Commun. 2004. PMID: 15033485
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