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BALB/c mice, but not C57BL/6 mice immunized with a ΔclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: association of protection with post-vaccination and post-challenge immune responses.
Twine S, Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W. Twine S, et al. Among authors: sjostedt a. Vaccine. 2012 May 21;30(24):3634-45. doi: 10.1016/j.vaccine.2012.03.036. Epub 2012 Apr 3. Vaccine. 2012. PMID: 22484348
A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine.
Twine S, Byström M, Chen W, Forsman M, Golovliov I, Johansson A, Kelly J, Lindgren H, Svensson K, Zingmark C, Conlan W, Sjöstedt A. Twine S, et al. Among authors: sjostedt a. Infect Immun. 2005 Dec;73(12):8345-52. doi: 10.1128/IAI.73.12.8345-8352.2005. Infect Immun. 2005. PMID: 16299332 Free PMC article.
191 results