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Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling.
Skardal A, Shupe T, Atala A. Skardal A, et al. Drug Discov Today. 2016 Sep;21(9):1399-1411. doi: 10.1016/j.drudis.2016.07.003. Epub 2016 Jul 12. Drug Discov Today. 2016. PMID: 27422270 Review.
Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function.
Skardal A, Smith L, Bharadwaj S, Atala A, Soker S, Zhang Y. Skardal A, et al. Biomaterials. 2012 Jun;33(18):4565-75. doi: 10.1016/j.biomaterials.2012.03.034. Epub 2012 Apr 2. Biomaterials. 2012. PMID: 22475531 Free PMC article.
Biomaterials for integration with 3-D bioprinting.
Skardal A, Atala A. Skardal A, et al. Ann Biomed Eng. 2015 Mar;43(3):730-46. doi: 10.1007/s10439-014-1207-1. Epub 2014 Dec 5. Ann Biomed Eng. 2015. PMID: 25476164 Review.
Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro.
Skardal A, Devarasetty M, Rodman C, Atala A, Soker S. Skardal A, et al. Ann Biomed Eng. 2015 Oct;43(10):2361-73. doi: 10.1007/s10439-015-1298-3. Epub 2015 Mar 17. Ann Biomed Eng. 2015. PMID: 25777294 Free PMC article.
A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs.
Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. Skardal A, et al. Acta Biomater. 2015 Oct;25:24-34. doi: 10.1016/j.actbio.2015.07.030. Epub 2015 Jul 22. Acta Biomater. 2015. PMID: 26210285
In situ patterned micro 3D liver constructs for parallel toxicology testing in a fluidic device.
Skardal A, Devarasetty M, Soker S, Hall AR. Skardal A, et al. Biofabrication. 2015 Sep 10;7(3):031001. doi: 10.1088/1758-5090/7/3/031001. Biofabrication. 2015. PMID: 26355538 Free PMC article.
Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology.
Deegan DB, Zimmerman C, Skardal A, Atala A, Shupe TD. Deegan DB, et al. Among authors: skardal a. J Mech Behav Biomed Mater. 2015 Mar;55:87-103. doi: 10.1016/j.jmbbm.2015.10.016. Epub 2015 Oct 30. J Mech Behav Biomed Mater. 2015. PMID: 26569044
A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening.
Skardal A, Devarasetty M, Forsythe S, Atala A, Soker S. Skardal A, et al. Biotechnol Bioeng. 2016 Sep;113(9):2020-32. doi: 10.1002/bit.25950. Epub 2016 Mar 8. Biotechnol Bioeng. 2016. PMID: 26888480 Free PMC article.
Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink.
Skardal A, Devarasetty M, Kang HW, Seol YJ, Forsythe SD, Bishop C, Shupe T, Soker S, Atala A. Skardal A, et al. J Vis Exp. 2016 Apr 21;(110):e53606. doi: 10.3791/53606. J Vis Exp. 2016. PMID: 27166839 Free PMC article.
Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors.
Zhang YS, Aleman J, Shin SR, Kilic T, Kim D, Mousavi Shaegh SA, Massa S, Riahi R, Chae S, Hu N, Avci H, Zhang W, Silvestri A, Sanati Nezhad A, Manbohi A, De Ferrari F, Polini A, Calzone G, Shaikh N, Alerasool P, Budina E, Kang J, Bhise N, Ribas J, Pourmand A, Skardal A, Shupe T, Bishop CE, Dokmeci MR, Atala A, Khademhosseini A. Zhang YS, et al. Among authors: skardal a. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2293-E2302. doi: 10.1073/pnas.1612906114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265064 Free PMC article.
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